Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 8446
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM249212(US9458105, I-10)
Affinity DataIC50: 7.11nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM249208(US9458105, I-6)
Affinity DataIC50: 14.2nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM249205(US9458105, I-3)
Affinity DataIC50: 366nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM249204(US9458105, I-2)
Affinity DataIC50: 983nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM249207(US9458105, I-5)
Affinity DataIC50: 3.14E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM249203(US9458105, I-1)
Affinity DataIC50: 3.32E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM249209(US9458105, I-7)
Affinity DataIC50: 6.91E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM249206(US9458105, I-4)
Affinity DataIC50: 1.33E+4nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM249211(US9458105, I-9)
Affinity DataIC50: 5.23E+4nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM249210(US9458105, I-8)
Affinity DataIC50: 1.00E+5nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In DepthDetails
US Patent