Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 8274
LigandPNGBDBM238901(US9403827, 3)
Affinity DataIC50: 1.80nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238899(US9403827, 1)
Affinity DataIC50: 2nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238900(US9403827, 2)
Affinity DataIC50: 2.10nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238902(US9403827, 4)
Affinity DataIC50: 3.10nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238904(US9403827, 6)
Affinity DataIC50: 8.5nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238903(US9403827, 5)
Affinity DataIC50: 120nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238907(US9403827, 9)
Affinity DataIC50: 210nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238918(US9403827, 20)
Affinity DataIC50: 354nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238923(US9403827, 25)
Affinity DataIC50: 356nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238909(US9403827, 11)
Affinity DataIC50: 371nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238921(US9403827, 23)
Affinity DataIC50: 385nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238910(US9403827, 12)
Affinity DataIC50: 414nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238908(US9403827, 10)
Affinity DataIC50: 432nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238906(US9403827, 8)
Affinity DataIC50: 447nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238913(US9403827, 15)
Affinity DataIC50: 451nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238912(US9403827, 14)
Affinity DataIC50: 473nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238905(US9403827, 7)
Affinity DataIC50: 531nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238920(US9403827, 22)
Affinity DataIC50: 587nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238911(US9403827, 13)
Affinity DataIC50: 724nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238922(US9403827, 24)
Affinity DataIC50: 748nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238900(US9403827, 2)
Affinity DataIC50: 779nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238899(US9403827, 1)
Affinity DataIC50: 882nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238917(US9403827, 19)
Affinity DataIC50: 930nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238901(US9403827, 3)
Affinity DataIC50: 1.45E+3nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238899(US9403827, 1)
Affinity DataIC50: 1.51E+3nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238915(US9403827, 17)
Affinity DataIC50: 1.67E+3nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238900(US9403827, 2)
Affinity DataIC50: 2.13E+3nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238916(US9403827, 18)
Affinity DataIC50: 2.91E+3nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238914(US9403827, 16)
Affinity DataIC50: 3.11E+3nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238919(US9403827, 21)
Affinity DataIC50: 4.30E+3nMT: 2°CAssay Description:Assay 2: For selected compounds displaying IC50s between 0.05 and 5 nM on MDM2, a slightly modified assay is used with the following adaptations: 0.1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238904(US9403827, 6)
Affinity DataIC50: 1.40E+4nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM238902(US9403827, 4)
Affinity DataIC50: 1.67E+4nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
In DepthDetails
US Patent