Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 8038
TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM230876(US10045974, 12 | US9346797, 12 | US10603310, Compo...)
Affinity DataKi:  6.10nM ΔG°:  -46.9kJ/molepH: 4.5 T: 2°CAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM230869(US10045974, 13 | US9346797, 13 | US9346797, 5 | US...)
Affinity DataKi:  6.70nM ΔG°:  -46.7kJ/molepH: 4.5 T: 2°CAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM230873(US9346797, 9)
Affinity DataKi:  6.90nM ΔG°:  -46.6kJ/molepH: 4.5 T: 2°CAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM230871(US10045974, 7 | US9346797, 7 | US10603310, Compoun...)
Affinity DataKi:  7.40nM ΔG°:  -46.4kJ/molepH: 4.5 T: 2°CAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM228170(BDBM230875 | US10045974, 11 | (S)-N-(3-(6-amino-2-...)
Affinity DataKi:  7.80nM ΔG°:  -46.3kJ/molepH: 4.5 T: 2°CAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM230867(US10045974, 14 | US9346797, 14 | US9346797, 3 | US...)
Affinity DataKi:  8.5nM ΔG°:  -46.1kJ/molepH: 4.5 T: 2°CAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM230869(US10045974, 13 | US9346797, 13 | US9346797, 5 | US...)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/molepH: 4.5 T: 2°CAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM230874(US10045974, 10 | US9346797, 10 | US10603310, Compo...)
Affinity DataKi:  16nM ΔG°:  -44.5kJ/molepH: 4.5 T: 2°CAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM230865(US10045974, 1 | US9346797, 1 | US10603310, Compoun...)
Affinity DataKi:  18nM ΔG°:  -44.2kJ/molepH: 4.5 T: 2°CAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM230867(US10045974, 14 | US9346797, 14 | US9346797, 3 | US...)
Affinity DataKi:  18nM ΔG°:  -44.2kJ/molepH: 4.5 T: 2°CAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM230868(US10045974, 4 | US9346797, 4 | US10603310, Compoun...)
Affinity DataKi:  20nM ΔG°:  -43.9kJ/molepH: 4.5 T: 2°CAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM230870(US10045974, 6 | US9346797, 6 | US10603310, Compoun...)
Affinity DataKi:  20nM ΔG°:  -43.9kJ/molepH: 4.5 T: 2°CAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM230866(US10045974, 2 | US9346797, 2 | US10603310, Compoun...)
Affinity DataKi:  23nM ΔG°:  -43.6kJ/molepH: 4.5 T: 2°CAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM230872(US10045974, 8 | US9346797, 8 | US10603310, Compoun...)
Affinity DataKi:  71nM ΔG°:  -40.8kJ/molepH: 4.5 T: 2°CAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent