Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 7832
TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221684(US9314464, 5 | US9593100, Compound 5 | US10568884,...)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221688(US9314464, 9 | US9593100, Compound 9 | US10568884,...)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221690(US9314464, 11 | US9593100, Compound 11 | US1056888...)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221689(US9314464, 10 | US9593100, Compound 10 | US1056888...)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221686(US9314464, 7 | US9593100, Compound 7 | US10568884,...)
Affinity DataIC50: 0.700nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221681(US9314464, 2 | US9593100, Compound 2 | US10568884,...)
Affinity DataIC50: 0.800nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221710(US9314464, 31 | US9593100, Compound 31 | US1056888...)
Affinity DataIC50: 0.800nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221699(US9314464, 20 | US9593100, Compound 20 | US1056888...)
Affinity DataIC50: 0.800nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221691(US9314464, 12 | US9593100, Compound 12 | US1056888...)
Affinity DataIC50: 0.950nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221692(US9314464, 13 | US9593100, Compound 13 | US1056888...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221694(US9314464, 15 | US9593100, Compound 15 | US1056888...)
Affinity DataIC50: 1.10nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221705(US9314464, 26 | US9593100, Compound 26 | US1056888...)
Affinity DataIC50: 1.70nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221683(US9314464, 4 | US9593100, Compound 4 | US10568884,...)
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221713(US9314464, 34 | US9593100, Compound 34 | US1056888...)
Affinity DataIC50: 2.70nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221711(US9314464, 32 | US9593100, Compound 32 | US1056888...)
Affinity DataIC50: 2.90nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221685(US9314464, 6 | US9593100, Compound 6 | US10568884,...)
Affinity DataIC50: 3.90nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221709(US9314464, 30 | US9593100, Compound 30 | US1056888...)
Affinity DataIC50: 4.30nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221698(US9314464, 19 | US9593100, Compound 19 | US1056888...)
Affinity DataIC50: 6.10nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221708(US9314464, 29 | US9593100, Compound 29 | US1056888...)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221695(US9314464, 16 | US9593100, Compound 16 | US1056888...)
Affinity DataIC50: 24nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221707(US9314464, 28 | US9593100, Compound 28 | US1056888...)
Affinity DataIC50: 90nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandPNGBDBM221706(US9314464, 27 | US9593100, Compound 27 | US1056888...)
Affinity DataIC50: 390nMpH: 7.5 T: 2°CAssay Description:B-Raf (V600E; 4 μM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent