Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 7714
TargetCytochrome P450 2C9(Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM26261(CHEMBL512283 | (2S)-3-(4-chloro-3-fluorophenoxy)-N...)
Affinity DataIC50: 1.30E+3nMT: 2°CAssay Description:P450 enzyme inhibition was measured using human cDNA-expressed CYP3A4, 2D6, 2C19, 2C9, and 1A2 recombinant enzymes and fluorogenic substrates (coumar...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 2C19(Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM26261(CHEMBL512283 | (2S)-3-(4-chloro-3-fluorophenoxy)-N...)
Affinity DataIC50: 2.40E+3nMT: 2°CAssay Description:P450 enzyme inhibition was measured using human cDNA-expressed CYP3A4, 2D6, 2C19, 2C9, and 1A2 recombinant enzymes and fluorogenic substrates (coumar...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 2D6(Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM26261(CHEMBL512283 | (2S)-3-(4-chloro-3-fluorophenoxy)-N...)
Affinity DataIC50: 1.77E+4nMT: 2°CAssay Description:P450 enzyme inhibition was measured using human cDNA-expressed CYP3A4, 2D6, 2C19, 2C9, and 1A2 recombinant enzymes and fluorogenic substrates (coumar...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 3A4(Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM26261(CHEMBL512283 | (2S)-3-(4-chloro-3-fluorophenoxy)-N...)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:P450 enzyme inhibition was measured using human cDNA-expressed CYP3A4, 2D6, 2C19, 2C9, and 1A2 recombinant enzymes and fluorogenic substrates (coumar...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 2C9(Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM26261(CHEMBL512283 | (2S)-3-(4-chloro-3-fluorophenoxy)-N...)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:P450 enzyme inhibition was measured using human cDNA-expressed CYP3A4, 2D6, 2C19, 2C9, and 1A2 recombinant enzymes and fluorogenic substrates (coumar...More data for this Ligand-Target Pair
In DepthDetails
US Patent