Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 7636
TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandPNGBDBM50078321(CHEMBL3414711 | US9260455, 7)
Affinity DataIC50: 118nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandPNGBDBM207626(US9260455, 5)
Affinity DataIC50: 274nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandPNGBDBM207626(US9260455, 5)
Affinity DataIC50: 613nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandPNGBDBM50078320(CHEMBL3414700 | US9260455, 4)
Affinity DataIC50: 672nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandPNGBDBM50078349(CHEMBL3414707 | US9260455, 3)
Affinity DataIC50: 704nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandPNGBDBM207627(US9260455, 6)
Affinity DataIC50: 718nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandPNGBDBM50081643(CHEMBL3422240 | US9260455, 2)
Affinity DataIC50: 737nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandPNGBDBM207625(US9260455, 1)
Affinity DataIC50: 805nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIsoform D of Beta-secretase 1 (BACE-I-432)(Human)
Pfizer

US Patent
LigandPNGBDBM50078324(CHEMBL3414708 | US9260455, 8)
Affinity DataIC50: 855nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandPNGBDBM50078349(CHEMBL3414707 | US9260455, 3)
Affinity DataIC50: 1.14E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandPNGBDBM207625(US9260455, 1)
Affinity DataIC50: 1.56E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandPNGBDBM50078324(CHEMBL3414708 | US9260455, 8)
Affinity DataIC50: 1.63E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandPNGBDBM50078320(CHEMBL3414700 | US9260455, 4)
Affinity DataIC50: 2.14E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandPNGBDBM50081643(CHEMBL3422240 | US9260455, 2)
Affinity DataIC50: 2.31E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandPNGBDBM207627(US9260455, 6)
Affinity DataIC50: 5.08E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In DepthDetails
US Patent