Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 7542
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200557(US9227973, 1)
Affinity DataIC50: 0.930nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200568(US9227973, 7B)
Affinity DataIC50: 4.5nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200559(US9227973, 3)
Affinity DataIC50: 6.30nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200561(US9227973, 6 isomer A | US9227973, 5 isomer A)
Affinity DataIC50: 22nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200564(US9227973, 8C)
Affinity DataIC50: 22nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay C): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200560(US9227973, 4)
Affinity DataIC50: 65nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200561(US9227973, 6 isomer A | US9227973, 5 isomer A)
Affinity DataIC50: 78nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200566(US9227973, 6 isomer B | US9227973, 5 isomer B)
Affinity DataIC50: 150nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200558(US9227973, 2)
Affinity DataIC50: 290nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200563(US9227973, 7A)
Affinity DataIC50: 380nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200565(US9227973, 9 isomer C | US9227973, 9 isomer B | BD...)
Affinity DataIC50: 480nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay C): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200569(US9227973, 8 isomer D)
Affinity DataIC50: 570nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay C): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200565(US9227973, 9 isomer C | US9227973, 9 isomer B | BD...)
Affinity DataIC50: 1.10E+3nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay C): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200565(US9227973, 9 isomer C | US9227973, 9 isomer B | BD...)
Affinity DataIC50: 1.10E+3nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay C): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200565(US9227973, 9 isomer C | US9227973, 9 isomer B | BD...)
Affinity DataIC50: 1.90E+3nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay C): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200566(US9227973, 6 isomer B | US9227973, 5 isomer B)
Affinity DataIC50: 4.60E+3nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In DepthDetails
US Patent