Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 7495
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197952(US9216997, compound 28-7)
Affinity DataIC50: 1.20nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197959(US9216997, compound 28-14)
Affinity DataIC50: 9.60nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197973(US9216997, Compound 89-1)
Affinity DataIC50: 10nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197953(US9216997, compound 28-8)
Affinity DataIC50: 10.9nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197954(US9216997, compound 28-9)
Affinity DataIC50: 11nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197955(US9216997, compound 28-10)
Affinity DataIC50: 13nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197947(US9216997, compound 28-2)
Affinity DataIC50: 18nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197939(US9216997, compound 8-1)
Affinity DataIC50: 19nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197974(US9216997, Compound 89-3)
Affinity DataIC50: 19nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197975(US9216997, Compound 89-4)
Affinity DataIC50: 28nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197967(US9216997, compound 53-1)
Affinity DataIC50: 29nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197949(US9216997, compound 28-4)
Affinity DataIC50: 33nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197948(US9216997, compound 28-3)
Affinity DataIC50: 34nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197976(US9216997, Compound 89-5)
Affinity DataIC50: 34nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197961(US9216997, compound 35-1)
Affinity DataIC50: 38nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197968(US9216997, compound 53-2)
Affinity DataIC50: 43nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197951(US9216997, compound 28-6)
Affinity DataIC50: 47nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197964(US9216997, compound 39-1)
Affinity DataIC50: 52nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197977(US9216997, compound 39-2)
Affinity DataIC50: 56nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM197960(US9216997, compound 28-15)
Affinity DataIC50: 68nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataIC50: 72nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent