Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 7265
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185584(US9156852, 1 | USRE47451, Example 1)
Affinity DataIC50: 1nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185584(US9156852, 1 | USRE47451, Example 1)
Affinity DataIC50: 2nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185589(US9156852, 83 | USRE47451, Example 83)
Affinity DataIC50: 4nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50: 5nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185584(US9156852, 1 | USRE47451, Example 1)
Affinity DataIC50: 5nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185589(US9156852, 83 | USRE47451, Example 83)
Affinity DataIC50: 5nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185586(US9156852, 38 | USRE47451, Example 38)
Affinity DataIC50: 5nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185585(US9156852, 16 | USRE47451, Example 16)
Affinity DataIC50: 5nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185589(US9156852, 83 | USRE47451, Example 83)
Affinity DataIC50: 5nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185588(US9156852, 59 | USRE47451, Example 59)
Affinity DataIC50: 6nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185588(US9156852, 59 | USRE47451, Example 59)
Affinity DataIC50: 7nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185589(US9156852, 83 | USRE47451, Example 83)
Affinity DataIC50: 7nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50: 7nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185586(US9156852, 38 | USRE47451, Example 38)
Affinity DataIC50: 9nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50: 10nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185589(US9156852, 83 | USRE47451, Example 83)
Affinity DataIC50: 10nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185589(US9156852, 83 | USRE47451, Example 83)
Affinity DataIC50: 12nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185590(US9156852, 105 | USRE47451, Example 105)
Affinity DataIC50: 15nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185585(US9156852, 16 | USRE47451, Example 16)
Affinity DataIC50: 15nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185584(US9156852, 1 | USRE47451, Example 1)
Affinity DataIC50: 22nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185584(US9156852, 1 | USRE47451, Example 1)
Affinity DataIC50: 23nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50: 23nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185587(US9156852, 50 | USRE47451, Example 50)
Affinity DataIC50: 26nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185590(US9156852, 105 | USRE47451, Example 105)
Affinity DataIC50: 31nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185587(US9156852, 50 | USRE47451, Example 50)
Affinity DataIC50: 32nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185585(US9156852, 16 | USRE47451, Example 16)
Affinity DataIC50: 32nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185586(US9156852, 38 | USRE47451, Example 38)
Affinity DataIC50: 40nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185588(US9156852, 59 | USRE47451, Example 59)
Affinity DataIC50: 42nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50: 44nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185590(US9156852, 105 | USRE47451, Example 105)
Affinity DataIC50: 50nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50: 56nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185586(US9156852, 38 | USRE47451, Example 38)
Affinity DataIC50: 57nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185586(US9156852, 38 | USRE47451, Example 38)
Affinity DataIC50: 66nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185590(US9156852, 105 | USRE47451, Example 105)
Affinity DataIC50: 71nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185586(US9156852, 38 | USRE47451, Example 38)
Affinity DataIC50: 93nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185584(US9156852, 1 | USRE47451, Example 1)
Affinity DataIC50: 121nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185587(US9156852, 50 | USRE47451, Example 50)
Affinity DataIC50: 128nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185590(US9156852, 105 | USRE47451, Example 105)
Affinity DataIC50: 179nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM185590(US9156852, 105 | USRE47451, Example 105)
Affinity DataIC50: 181nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails
US Patent