Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 6955
TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataKd:  20nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
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TargetMitogen-activated protein kinase 12(Human)
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LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataKd:  43nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
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TargetTyrosine-protein kinase HCK(Human)
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LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataKd:  8nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
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TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataKd:  10nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
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TargetTyrosine-protein kinase SYK(Human)
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LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataKd:  14nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 alpha(Human)
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LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataKd:  2.00E+4nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
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TargetGlycogen synthase kinase-3 beta(Human)
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LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataKd:  1.20E+3nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
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US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataIC50: 22nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
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US Patent

TargetMitogen-activated protein kinase 14(Human)
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LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataIC50: 60nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
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US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataIC50: 334nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
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US Patent

TargetMitogen-activated protein kinase 12(Human)
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LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataIC50: 3.74E+3nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
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US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataIC50: 1.70E+4nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
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US Patent