Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 7045
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Emory University

US Patent
LigandPNGBDBM168626(US9079852, Table F, Compound 11)
Affinity DataIC50: 100nMAssay Description:Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Emory University

US Patent
LigandPNGBDBM168624(US9079852, Table F, Compound 9)
Affinity DataIC50: 100nMAssay Description:Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Emory University

US Patent
LigandPNGBDBM168625(US9079852, Table F, Compound 10)
Affinity DataIC50: 150nMAssay Description:Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Emory University

US Patent
LigandPNGBDBM168620(US9079852, Table F, Compound 5)
Affinity DataIC50: 300nMAssay Description:Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Emory University

US Patent
LigandPNGBDBM168619(US9079852, Table F, Compound 4)
Affinity DataIC50: 340nMAssay Description:Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Emory University

US Patent
LigandPNGBDBM168622(US9079852, Table F, Compound 7)
Affinity DataIC50: 350nMAssay Description:Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Emory University

US Patent
LigandPNGBDBM168621(US9079852, Table F, Compound 6)
Affinity DataIC50: 350nMAssay Description:Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Emory University

US Patent
LigandPNGBDBM168618(US9079852, Table F, Compound 3)
Affinity DataIC50: 350nMAssay Description:Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Emory University

US Patent
LigandPNGBDBM168617(US9079852, Table F, Compound 2)
Affinity DataIC50: 620nMAssay Description:Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Emory University

US Patent
LigandPNGBDBM168616(US9079852, Table F, Compound 1)
Affinity DataIC50: 720nMAssay Description:Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

US Patent
LigandPNGBDBM168618(US9079852, Table F, Compound 3)
Affinity DataKi:  553nMAssay Description:Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

US Patent
LigandPNGBDBM168620(US9079852, Table F, Compound 5)
Affinity DataKi:  1.00E+3nMAssay Description:Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

US Patent
LigandPNGBDBM168617(US9079852, Table F, Compound 2)
Affinity DataKi:  1.60E+3nMAssay Description:Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

US Patent
LigandPNGBDBM168626(US9079852, Table F, Compound 11)
Affinity DataKi:  5.00E+3nMAssay Description:Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

US Patent
LigandPNGBDBM168625(US9079852, Table F, Compound 10)
Affinity DataKi:  7.50E+3nMAssay Description:Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

US Patent
LigandPNGBDBM168622(US9079852, Table F, Compound 7)
Affinity DataKi:  7.50E+3nMAssay Description:Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

US Patent
LigandPNGBDBM168621(US9079852, Table F, Compound 6)
Affinity DataKi:  7.50E+3nMAssay Description:Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

US Patent
LigandPNGBDBM168624(US9079852, Table F, Compound 9)
Affinity DataKi:  1.00E+4nMAssay Description:Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

US Patent
LigandPNGBDBM168619(US9079852, Table F, Compound 4)
Affinity DataKi:  1.30E+4nMAssay Description:Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

US Patent
LigandPNGBDBM168616(US9079852, Table F, Compound 1)
Affinity DataKi:  3.90E+4nMAssay Description:Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
Go to US Patent