Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 7006
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165927(US9067931, 75 | US10214524, Example 75)
Affinity DataKi: <0.100nM ΔG°: <-53.1kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
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US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165926(US9067931, 73 | US10214524, Example 73)
Affinity DataKi: <1nM ΔG°: <-47.8kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165925(US9067931, 20 | US10214524, Example 20)
Affinity DataKi:  1.60nM ΔG°:  -46.7kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165935(US9067931, 154 | US10214524, Example 154)
Affinity DataKi:  3nM ΔG°:  -45.2kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165928(US9067931, 76 | US10214524, Example 76)
Affinity DataKi:  3.30nM ΔG°:  -45.0kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165937(US9067931, 175 | US10214524, Example 175)
Affinity DataKi:  8.30nM ΔG°:  -42.9kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165929(US9067931, 90 | US10214524, Example 90)
Affinity DataKi:  14nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165936(US9067931, 163 | US10214524, Example 163)
Affinity DataKi:  14nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165923(US9067931, 17 | US10214524, Example 17)
Affinity DataKi:  17nM ΔG°:  -41.2kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165930(US9067931, 108 | US10214524, Example 108)
Affinity DataKi:  17nM ΔG°:  -41.2kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165931(US9067931, 116 | US10214524, Example 116)
Affinity DataKi:  17nM ΔG°:  -41.2kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165924(US9067931, 19 | US10214524, Example 19)
Affinity DataKi:  20nM ΔG°:  -40.8kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165922(US9067931, 4 | US10214524, Example 4)
Affinity DataKi:  24nM ΔG°:  -40.4kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM50393246(CHEMBL2151440 | US9067931, 130 | US10214524, Examp...)
Affinity DataKi:  26nM ΔG°:  -40.2kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165933(US9067931, 150 | US10214524, Example 150)
Affinity DataKi:  35nM ΔG°:  -39.6kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165921(US9067931, 3 | US10214524, Example 3)
Affinity DataKi:  60nM ΔG°:  -38.3kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM50393246(CHEMBL2151440 | US9067931, 130 | US10214524, Examp...)
Affinity DataKi:  62nM ΔG°:  -38.2kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165934(US9067931, 151 | US10214524, Example 151)
Affinity DataKi:  88nM ΔG°:  -37.4kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165932(US9067931, 149 | US10214524, Example 149)
Affinity DataKi:  97nM ΔG°:  -37.2kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165938(US9067931, 186 | US10214524, Example 186)
Affinity DataKi:  120nM ΔG°:  -36.7kJ/molepH: 7.4 T: 2°CAssay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails
US Patent