Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 6951
TargetAmine oxidase [flavin-containing] B(Rat)
Newron Pharmaceuticals

US Patent
LigandPNGBDBM19187(CHEMBL396778 | (2S)-2-[({4-[(3-fluorophenyl)methox...)
Affinity DataIC50: 100nMpH: 7.4Assay Description:The enzyme activity was assessed with a radioenzymatic assay using the substrate 14C-phenylethylamine (PEA) specific for MAO-B.The mitochondrial pell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
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TargetAmine oxidase [flavin-containing] B(Rat)
Newron Pharmaceuticals

US Patent
LigandPNGBDBM161094(US9051240, (S)-(+)-2-[4-(2-Fluorobenzyloxy)-benzyl...)
Affinity DataIC50: 200nMpH: 7.4Assay Description:The enzyme activity was assessed with a radioenzymatic assay using the substrate 14C-phenylethylamine (PEA) specific for MAO-B.The mitochondrial pell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Rat)
Newron Pharmaceuticals

US Patent
LigandPNGBDBM161089(US9051240, 2-[2-(3-Butoxyphenyl)-ethylamino]-N-met...)
Affinity DataIC50: 1.10E+5nMpH: 7.4Assay Description:The enzyme activity was assessed with a radioenzymatic assay using the substrate 14C-phenylethylamine (PEA) specific for MAO-B.The mitochondrial pell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Rat)
Newron Pharmaceuticals

US Patent
LigandPNGBDBM161090(US9447029, 2-[2-(3-Butoxyphenyl)-ethylamino]-N,N-d...)
Affinity DataIC50: 2.31E+5nMpH: 7.4Assay Description:The enzyme activity was assessed with a radioenzymatic assay using the substrate 14C-phenylethylamine (PEA) specific for MAO-B.The mitochondrial pell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Rat)
Newron Pharmaceuticals

US Patent
LigandPNGBDBM161091(US9051240, 2-[2-(3-Butoxy-2,6-difluorophenyl)-ethy...)
Affinity DataIC50: 3.00E+5nMpH: 7.4Assay Description:The enzyme activity was assessed with a radioenzymatic assay using the substrate 14C-phenylethylamine (PEA) specific for MAO-B.The mitochondrial pell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Rat)
Newron Pharmaceuticals

US Patent
LigandPNGBDBM161092(US9051240, 2-[2-(3-Butoxy-4-methoxyphenyl)-ethylam...)
Affinity DataIC50: 3.00E+5nMpH: 7.4Assay Description:The enzyme activity was assessed with a radioenzymatic assay using the substrate 14C-phenylethylamine (PEA) specific for MAO-B.The mitochondrial pell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Rat)
Newron Pharmaceuticals

US Patent
LigandPNGBDBM161093(US9447029, 2-[2-(3-Butoxyphenyl)-ethylamino]-N,N-d...)
Affinity DataIC50: 3.00E+5nMpH: 7.4Assay Description:The enzyme activity was assessed with a radioenzymatic assay using the substrate 14C-phenylethylamine (PEA) specific for MAO-B.The mitochondrial pell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
Go to US Patent