Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 6933
TargetVascular endothelial growth factor receptor 2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50262685(CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...)
Affinity DataIC50: 25.1nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
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TargetActivin receptor type-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM36356(DMH3 | N,N-dimethyl-3-(4- (3-(quinolin-4-yl)pyrazo...)
Affinity DataIC50: 26.7nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
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TargetActivin receptor type-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM160333(US9040694, 5)
Affinity DataIC50: 40.7nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
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TargetActivin receptor type-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM36355(DMH2 | 4-(2-(4-(3-(quinolin-4-yl)pyrazolo[1,5-a]py...)
Affinity DataIC50: 42.8nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
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TargetActivin receptor type-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM36354(DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...)
Affinity DataIC50: 108nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
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TargetActivin receptor type-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50262685(CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...)
Affinity DataIC50: 148nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
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PDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM160333(US9040694, 5)
Affinity DataIC50: 215nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM5410(4-[2-(4-{3-phenylpyrazolo[1,5-a]pyrimidin-6-yl}phe...)
Affinity DataIC50: 235nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
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Target5'-AMP-activated protein kinase subunit beta-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50262685(CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...)
Affinity DataIC50: 318nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
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Target5'-AMP-activated protein kinase subunit beta-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM36355(DMH2 | 4-(2-(4-(3-(quinolin-4-yl)pyrazolo[1,5-a]py...)
Affinity DataIC50: 527nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
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TargetTGF-beta receptor type-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM160333(US9040694, 5)
Affinity DataIC50: 565nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
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TargetTGF-beta receptor type-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM36356(DMH3 | N,N-dimethyl-3-(4- (3-(quinolin-4-yl)pyrazo...)
Affinity DataIC50: 999nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
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Target5'-AMP-activated protein kinase subunit beta-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM160333(US9040694, 5)
Affinity DataIC50: 1.12E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
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TargetTGF-beta receptor type-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM36355(DMH2 | 4-(2-(4-(3-(quinolin-4-yl)pyrazolo[1,5-a]py...)
Affinity DataIC50: 1.58E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
Go to US Patent

Target5'-AMP-activated protein kinase subunit beta-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM36356(DMH3 | N,N-dimethyl-3-(4- (3-(quinolin-4-yl)pyrazo...)
Affinity DataIC50: 1.94E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM36356(DMH3 | N,N-dimethyl-3-(4- (3-(quinolin-4-yl)pyrazo...)
Affinity DataIC50: 2.06E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM36355(DMH2 | 4-(2-(4-(3-(quinolin-4-yl)pyrazolo[1,5-a]py...)
Affinity DataIC50: 2.42E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
Go to US Patent

TargetActivin receptor type-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM5410(4-[2-(4-{3-phenylpyrazolo[1,5-a]pyrimidin-6-yl}phe...)
Affinity DataIC50: 2.57E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
Go to US Patent

Target5'-AMP-activated protein kinase subunit beta-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM5410(4-[2-(4-{3-phenylpyrazolo[1,5-a]pyrimidin-6-yl}phe...)
Affinity DataIC50: 2.92E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50262685(CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...)
Affinity DataIC50: 1.08E+4nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
Go to US Patent