Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 6905
TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158387(US9029381, 29)
Affinity DataIC50: 0.834nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158386(US9029381, 28)
Affinity DataIC50: 1.37nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158358(US9029381, 12 | US9029381, 11 | US9029381, 10)
Affinity DataIC50: 1.63nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158350(US9029381, 24 | US9029381, 4)
Affinity DataIC50: 3.41nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158350(US9029381, 24 | US9029381, 4)
Affinity DataIC50: 3.49nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158389(US9029381, 32 | US9029381, 31)
Affinity DataIC50: 3.69nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158403(US9029381, 44 | US9029381, 43 | US9029381, 42)
Affinity DataIC50: 3.81nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158395(US9029381, 34)
Affinity DataIC50: 5.09nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158403(US9029381, 44 | US9029381, 43 | US9029381, 42)
Affinity DataIC50: 5.83nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158397(US9029381, 37 | US9029381, 36)
Affinity DataIC50: 6.19nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158350(US9029381, 24 | US9029381, 4)
Affinity DataIC50: 6.40nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158362(US9029381, 14 | US9029381, 13)
Affinity DataIC50: 6.81nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158385(US9029381, 27)
Affinity DataIC50: 7.30nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158356(US9029381, 8)
Affinity DataIC50: 7.56nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158388(US9029381, 30)
Affinity DataIC50: 8.59nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158358(US9029381, 12 | US9029381, 11 | US9029381, 10)
Affinity DataIC50: 10.2nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158399(US9029381, 39 | US9029381, 38)
Affinity DataIC50: 11.6nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158362(US9029381, 14 | US9029381, 13)
Affinity DataIC50: 13.3nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158354(US9029381, 6)
Affinity DataIC50: 14nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158403(US9029381, 44 | US9029381, 43 | US9029381, 42)
Affinity DataIC50: 14.4nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158362(US9029381, 14 | US9029381, 13)
Affinity DataIC50: 16.8nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158373(US9029381, 23 | US9029381, 22 | US9029381, 21)
Affinity DataIC50: 17.5nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158401(US9029381, 41 | US9029381, 40)
Affinity DataIC50: 18.2nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158373(US9029381, 23 | US9029381, 22 | US9029381, 21)
Affinity DataIC50: 20.2nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158408(US9029381, 46)
Affinity DataIC50: 20.2nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158347(US9029381, 1)
Affinity DataIC50: 21.3nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158395(US9029381, 34)
Affinity DataIC50: 23.9nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158372(US9029381, 20)
Affinity DataIC50: 29.1nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158373(US9029381, 23 | US9029381, 22 | US9029381, 21)
Affinity DataIC50: 30.4nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158372(US9029381, 20)
Affinity DataIC50: 33.9nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158355(US9029381, 7)
Affinity DataIC50: 39.7nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158353(US9029381, 5)
Affinity DataIC50: 44.7nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158357(US9029381, 9)
Affinity DataIC50: 45.3nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158370(US9029381, 18)
Affinity DataIC50: 62.5nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158381(US9029381, 26)
Affinity DataIC50: 88.3nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158348(US9029381, 2)
Affinity DataIC50: 105nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158406(US9029381, 45)
Affinity DataIC50: 127nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158355(US9029381, 7)
Affinity DataIC50: 146nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158369(US9029381, 17)
Affinity DataIC50: 197nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158367(US9029381, 15)
Affinity DataIC50: 262nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158371(US9029381, 19)
Affinity DataIC50: 351nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158369(US9029381, 17)
Affinity DataIC50: 433nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158368(US9029381, 16)
Affinity DataIC50: 441nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158401(US9029381, 41 | US9029381, 40)
Affinity DataIC50: 733nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158403(US9029381, 44 | US9029381, 43 | US9029381, 42)
Affinity DataIC50: 834nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158380(US9029381, 25)
Affinity DataIC50: 870nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158397(US9029381, 37 | US9029381, 36)
Affinity DataIC50: 1.05E+3nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158358(US9029381, 12 | US9029381, 11 | US9029381, 10)
Affinity DataIC50: 1.63E+3nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158399(US9029381, 39 | US9029381, 38)
Affinity DataIC50: 1.80E+3nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158373(US9029381, 23 | US9029381, 22 | US9029381, 21)
Affinity DataIC50: 2.60E+3nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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