Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 6819
Target5,6-dihydroxyindole-2-carboxylic acid oxidase(Mouse)
Galderma Research & Development

US Patent
LigandPNGBDBM152929(US8993596, Compound 24)
Affinity DataIC50: 150nMpH: 6.8 T: 2°CAssay Description:The activity of the inhibitors is measured using a lysate of B16F1 cells (murine melanoma line). In the presence of the L-tyrosine substrate, the tyr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5,6-dihydroxyindole-2-carboxylic acid oxidase(Mouse)
Galderma Research & Development

US Patent
LigandPNGBDBM152928(US8993596, Compound 48)
Affinity DataIC50: 200nMpH: 6.8 T: 2°CAssay Description:The activity of the inhibitors is measured using a lysate of B16F1 cells (murine melanoma line). In the presence of the L-tyrosine substrate, the tyr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5,6-dihydroxyindole-2-carboxylic acid oxidase(Mouse)
Galderma Research & Development

US Patent
LigandPNGBDBM50248158(N-butylresorcinol | CHEMBL450195 | US8993596, 4-Bu...)
Affinity DataIC50: 3.00E+3nMpH: 6.8 T: 2°CAssay Description:The activity of the inhibitors is measured using a lysate of B16F1 cells (murine melanoma line). In the presence of the L-tyrosine substrate, the tyr...More data for this Ligand-Target Pair
In DepthDetails
US Patent