Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 6762
TargetCytochrome P450 3A4(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 150nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151584(US8987315, 4)
Affinity DataIC50: 210nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151583(US8987315, 3)
Affinity DataIC50: 270nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151586(US8987315, 1)
Affinity DataIC50: 400nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 400nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151582(US8987315, 2)
Affinity DataIC50: 460nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 2C9(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151583(US8987315, 3)
Affinity DataIC50: 4.80E+3nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 2C9(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151586(US8987315, 1)
Affinity DataIC50: 7.00E+3nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 2C9(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151584(US8987315, 4)
Affinity DataIC50: 1.50E+4nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 2C19(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 1.90E+4nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 2C9(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151582(US8987315, 2)
Affinity DataIC50: 2.70E+4nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 2C19(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151583(US8987315, 3)
Affinity DataIC50: 3.00E+4nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 2C19(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151584(US8987315, 4)
Affinity DataIC50: 3.50E+4nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 2C19(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151586(US8987315, 1)
Affinity DataIC50: 3.70E+4nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 2C9(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 4.00E+4nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 2C19(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151582(US8987315, 2)
Affinity DataIC50: 4.50E+4nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 3A4(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151582(US8987315, 2)
Affinity DataIC50: 6.00E+4nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 3A4(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151586(US8987315, 1)
Affinity DataIC50: 2.00E+5nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 3A4(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151583(US8987315, 3)
Affinity DataIC50: 2.00E+5nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 3A4(Human)
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM151584(US8987315, 4)
Affinity DataIC50: 2.00E+5nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:MeC...More data for this Ligand-Target Pair
In DepthDetails
US Patent