Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 6557
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101762(US8530490, 22)
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101764(US8530490, 24)
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101763(CHEMBL2057909 | US8530490, 23)
Affinity DataIC50: 50nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101745(US8530490, 5)
Affinity DataIC50: 60nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101748(CHEMBL2057911 | US8530490, 8)
Affinity DataIC50: 90nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101808(US8530490, 68)
Affinity DataIC50: 110nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101897(US8530490, 167)
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101801(US8530490, 61)
Affinity DataIC50: 140nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101787(US8530490, 47)
Affinity DataIC50: 210nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101793(US8530490, 53)
Affinity DataIC50: 230nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101794(US8530490, 54)
Affinity DataIC50: 230nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101761(US8530490, 21)
Affinity DataIC50: 270nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101798(US8530490, 58)
Affinity DataIC50: 310nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101909(US8530490, 1)
Affinity DataIC50: 330nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM5118(US8530490, 6 | US8530490, 49 | US8530490, 397)
Affinity DataIC50: 460nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101751(US8530490, 11)
Affinity DataIC50: 490nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM139105(US8883759, 19)
Affinity DataIC50: 610nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101747(US8530490, 7)
Affinity DataIC50: 640nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101799(US8530490, 59)
Affinity DataIC50: 720nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101809(US8530490, 69)
Affinity DataIC50: 740nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In DepthDetails
US Patent