Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 6457
TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130367(US8822534, Example 11-14)
Affinity DataIC50: 0.0700nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130365(US8822534, Example 12-1 | US8822534, Example 11-1 ...)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130366(US8822534, Example 11-11 | US8993631, 9-6)
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130360(US8822534, Example 5-46 | US8993631, 5-9)
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130362(US8822534, Example 5-55 | US8993631, 5-11)
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130359(US8822534, Example 5-39 | US8993631, 5-8)
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130369(US8822534, Example 14-1 | US8993631, 11-1)
Affinity DataIC50: 0.800nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130365(US8822534, Example 12-1 | US8822534, Example 11-1 ...)
Affinity DataIC50: 1.10nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130370(US8822534, Example 15-1 | US8993631, 12-1)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130358(US8822534, Example 5-37 | US8993631, 5-7)
Affinity DataIC50: 2.30nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130361(US8822534, Example 5-47 | US8993631, 5-10)
Affinity DataIC50: 2.70nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130356(US8822534, Example 5-11 | US8993631, 5-4)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130355(US8822534, Example 5-7 | US8993631, 5-3)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130354(US8822534, Example 5-4 | US8993631, 5-2)
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130352(US8822534, Example 3-27)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130351(US8822534, Example 3-26 | US8993631, 3-13)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130350(US8822534, Example 3-25 | US8993631, 3-12)
Affinity DataIC50: 18nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM7494(US8822534, Example 5-1 | US8822534, 5-36 | US89936...)
Affinity DataIC50: 38nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM7494(US8822534, Example 5-1 | US8822534, 5-36 | US89936...)
Affinity DataIC50: 42nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130364(US8822534, Example 9-1 | US8993631, 8-1)
Affinity DataIC50: 56nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130357(US8822534, Example 5-12 | US8993631, 5-5)
Affinity DataIC50: 67nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130363(US8822534, Example 6-1 | US8993631, 6-1)
Affinity DataIC50: 75nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In DepthDetails
US Patent