Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 6315
TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM122537(US8735593, I-5)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:Compounds of the present invention were screened for their ability to inhibit GSK-3β (AA 1-420) activity using a standard coupled enzyme system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
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TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM122535(US8735593, I-3)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Compounds of the present invention were screened for their ability to inhibit GSK-3β (AA 1-420) activity using a standard coupled enzyme system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
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TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM122533(US8735593, I-1)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Compounds of the present invention were screened for their ability to inhibit GSK-3β (AA 1-420) activity using a standard coupled enzyme system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
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TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM122534(US8735593, I-2)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:Compounds of the present invention were screened for their ability to inhibit GSK-3β (AA 1-420) activity using a standard coupled enzyme system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
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TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM122537(US8735593, I-5)
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:Compounds of the present invention were screened for their ability to inhibit GSK-3β (AA 1-420) activity using a standard coupled enzyme system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM122536(US8735593, I-4)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:Compounds of the present invention were screened for their ability to inhibit GSK-3β (AA 1-420) activity using a standard coupled enzyme system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM122535(US8735593, I-3)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:Compounds of the present invention were screened for their ability to inhibit GSK-3β (AA 1-420) activity using a standard coupled enzyme system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM122533(US8735593, I-1)
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:Compounds of the present invention were screened for their ability to inhibit GSK-3β (AA 1-420) activity using a standard coupled enzyme system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM122534(US8735593, I-2)
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:Compounds of the present invention were screened for their ability to inhibit GSK-3β (AA 1-420) activity using a standard coupled enzyme system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM122536(US8735593, I-4)
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:Compounds of the present invention were screened for their ability to inhibit GSK-3β (AA 1-420) activity using a standard coupled enzyme system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
Go to US Patent