Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 6225
TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118096(US8664219, I-16 | US8664219, I-8)
Affinity DataIC50: 0.300nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118098(US8664219, I-10)
Affinity DataIC50: 0.5nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118093(US8664219, I-3)
Affinity DataIC50: 0.700nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118094(US8664219, I-4)
Affinity DataIC50: 1nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118102(US8664219, I-18)
Affinity DataIC50: 1nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118097(US8664219, I-9)
Affinity DataIC50: 2nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118103(US8664219, I-19)
Affinity DataIC50: 2nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118105(US8664219, I-23)
Affinity DataIC50: 2nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118096(US8664219, I-16 | US8664219, I-8)
Affinity DataIC50: 3nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118101(US8664219, I-17)
Affinity DataIC50: 3nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118104(US8664219, I-21)
Affinity DataIC50: 3nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118098(US8664219, I-10)
Affinity DataIC50: 6nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118096(US8664219, I-16 | US8664219, I-8)
Affinity DataIC50: 10nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118093(US8664219, I-3)
Affinity DataIC50: 13nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118094(US8664219, I-4)
Affinity DataIC50: 20nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118103(US8664219, I-19)
Affinity DataIC50: 20nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118104(US8664219, I-21)
Affinity DataIC50: 20nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118105(US8664219, I-23)
Affinity DataIC50: 25nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118099(US8664219, I-15)
Affinity DataIC50: 30nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118095(US8664219, I-5)
Affinity DataIC50: 30nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118101(US8664219, I-17)
Affinity DataIC50: 30nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118097(US8664219, I-9)
Affinity DataIC50: 48nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118096(US8664219, I-16 | US8664219, I-8)
Affinity DataIC50: 83nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118099(US8664219, I-15)
Affinity DataIC50: 200nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118102(US8664219, I-18)
Affinity DataIC50: 300nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM118095(US8664219, I-5)
Affinity DataIC50: 800nMAssay Description:Compounds are screened for their ability to inhibit the phosphorylation of tyrosine (TYR) residues through the use of western blotting of Jurkat cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent