Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 6163
Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50314763(US8629154, 2(2) | CHEMBL1092241 | 9-methyl-2-(meth...)
Affinity DataIC50: 7.80nMAssay Description:Compounds of general formulas 1 and 2 were tested for their ability to prevent 5-HT6 receptors activation by serotonin. HEK 293 cells (cells of human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50314759(US8629154, 1.1(1) | CHEMBL1091206 | 2-(methylthio)...)
Affinity DataIC50: 27nMAssay Description:Compounds of general formulas 1 and 2 were tested for their ability to prevent 5-HT6 receptors activation by serotonin. HEK 293 cells (cells of human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50314762(US8629154, 1.2(3) | 5-methyl-2-(methylthio)-3-(phe...)
Affinity DataIC50: 32nMAssay Description:Compounds of general formulas 1 and 2 were tested for their ability to prevent 5-HT6 receptors activation by serotonin. HEK 293 cells (cells of human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50314760(CHEMBL1091207 | US8629154, 1.2(1) | 2-(methylthio)...)
Affinity DataIC50: 35nMAssay Description:Compounds of general formulas 1 and 2 were tested for their ability to prevent 5-HT6 receptors activation by serotonin. HEK 293 cells (cells of human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50314761(US8629154, 2(1) | CHEMBL1091208 | 2-Methylsulfanyl...)
Affinity DataIC50: 479nMAssay Description:Compounds of general formulas 1 and 2 were tested for their ability to prevent 5-HT6 receptors activation by serotonin. HEK 293 cells (cells of human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50314762(US8629154, 1.2(3) | 5-methyl-2-(methylthio)-3-(phe...)
Affinity DataKi:  0.440nM ΔG°:  -54.3kJ/mole IC50: 0.948nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50314759(US8629154, 1.1(1) | CHEMBL1091206 | 2-(methylthio)...)
Affinity DataKi:  0.458nM ΔG°:  -54.2kJ/mole IC50: 0.986nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50314760(CHEMBL1091207 | US8629154, 1.2(1) | 2-(methylthio)...)
Affinity DataKi:  0.549nM ΔG°:  -53.7kJ/mole IC50: 1.18nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50314763(US8629154, 2(2) | CHEMBL1092241 | 9-methyl-2-(meth...)
Affinity DataKi:  0.680nM ΔG°:  -53.2kJ/mole IC50: 1.46nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50314761(US8629154, 2(1) | CHEMBL1091208 | 2-Methylsulfanyl...)
Affinity DataKi:  7.97nM ΔG°:  -47.0kJ/mole IC50: 17.2nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
In DepthDetails
US Patent