Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 12973
TargetCytochrome P450 2D6(Human)
NRG Therapeutics

US Patent
LigandPNGBDBM746826((E)-N-(2-methyl-3-fluorophenyl)-3-(1H-indazol-6-yl...)
Affinity DataIC50: 74nMAssay Description:Studies to assess tested compound mediated inhibition of cytochrome P450 enzyme isoform CYP2D6 were performed using human liver microsomes (BD Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
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TargetCytochrome P450 2D6(Human)
NRG Therapeutics

US Patent
LigandPNGBDBM746831(US20250179028, Example 26)
Affinity DataIC50: 8.80E+3nMAssay Description:Studies to assess tested compound mediated inhibition of cytochrome P450 enzyme isoform CYP2D6 were performed using human liver microsomes (BD Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
NRG Therapeutics

US Patent
LigandPNGBDBM746830(US20250179028, Example 25)
Affinity DataIC50: 1.38E+4nMAssay Description:Studies to assess tested compound mediated inhibition of cytochrome P450 enzyme isoform CYP2D6 were performed using human liver microsomes (BD Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
NRG Therapeutics

US Patent
LigandPNGBDBM746827((E)-N-(3-fluoro-2-methylphenyl)-3-(2-oxo-2,3-dihyd...)
Affinity DataIC50: 1.90E+4nMAssay Description:Studies to assess tested compound mediated inhibition of cytochrome P450 enzyme isoform CYP2D6 were performed using human liver microsomes (BD Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
NRG Therapeutics

US Patent
LigandPNGBDBM746829((E)-N-(3-fluoro-2-methylphenyl)-3-(2-oxoindolin-6-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Studies to assess tested compound mediated inhibition of cytochrome P450 enzyme isoform CYP2D6 were performed using human liver microsomes (BD Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
NRG Therapeutics

US Patent
LigandPNGBDBM746828((E)-N-(3-fluoro-2-methylphenyl)-3-(1-methyl-2-oxo-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Studies to assess tested compound mediated inhibition of cytochrome P450 enzyme isoform CYP2D6 were performed using human liver microsomes (BD Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
Go to US Patent