Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 12886
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737446(US20250136618, Compound 2)
Affinity DataIC50: 13nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM595423(US11590142, Compound 13 | US20250136618, Compound ...)
Affinity DataIC50: 25nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737448(US20250136618, Compound 4)
Affinity DataIC50: 25nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737447(US20250136618, Compound 3)
Affinity DataIC50: 30nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA topoisomerase 4 subunit A/B(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737448(US20250136618, Compound 4)
Affinity DataIC50: 44nMAssay Description:E. coli topoisomerase IV decatenation activity and its inhibition was assayed using a kit procured from Inpiralis (D4002) and the kit protocol was ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA topoisomerase 4 subunit A/B(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737446(US20250136618, Compound 2)
Affinity DataIC50: 45nMAssay Description:E. coli topoisomerase IV decatenation activity and its inhibition was assayed using a kit procured from Inpiralis (D4002) and the kit protocol was ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA topoisomerase 4 subunit A/B(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM595423(US11590142, Compound 13 | US20250136618, Compound ...)
Affinity DataIC50: 50nMAssay Description:E. coli topoisomerase IV decatenation activity and its inhibition was assayed using a kit procured from Inpiralis (D4002) and the kit protocol was ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA topoisomerase 4 subunit A/B(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737447(US20250136618, Compound 3)
Affinity DataIC50: 50nMAssay Description:E. coli topoisomerase IV decatenation activity and its inhibition was assayed using a kit procured from Inpiralis (D4002) and the kit protocol was ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737451(US20250136618, Compound 7)
Affinity DataIC50: 67nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737454(US20250136618, Compound 10)
Affinity DataIC50: 70nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA topoisomerase 4 subunit A/B(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737454(US20250136618, Compound 10)
Affinity DataIC50: 78nMAssay Description:E. coli topoisomerase IV decatenation activity and its inhibition was assayed using a kit procured from Inpiralis (D4002) and the kit protocol was ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA topoisomerase 4 subunit A/B(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737453(US20250136618, Compound 9)
Affinity DataIC50: 91nMAssay Description:E. coli topoisomerase IV decatenation activity and its inhibition was assayed using a kit procured from Inpiralis (D4002) and the kit protocol was ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737452(US20250136618, Compound 8)
Affinity DataIC50: 95nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA topoisomerase 4 subunit A/B(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737449(US20250136618, Compound 5)
Affinity DataIC50: 110nMAssay Description:E. coli topoisomerase IV decatenation activity and its inhibition was assayed using a kit procured from Inpiralis (D4002) and the kit protocol was ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737450(US20250136618, Compound 6)
Affinity DataIC50: 120nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA topoisomerase 4 subunit A/B(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737450(US20250136618, Compound 6)
Affinity DataIC50: 130nMAssay Description:E. coli topoisomerase IV decatenation activity and its inhibition was assayed using a kit procured from Inpiralis (D4002) and the kit protocol was ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737453(US20250136618, Compound 9)
Affinity DataIC50: 170nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 233nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737449(US20250136618, Compound 5)
Affinity DataIC50: 320nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent

TargetDNA topoisomerase 4 subunit A/B(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 1.44E+4nMAssay Description:E. coli topoisomerase IV decatenation activity and its inhibition was assayed using a kit procured from Inpiralis (D4002) and the kit protocol was ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent