Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 12690
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720173(2-methyl-5-[5-methyl-4-({5H,6H,7H,8H-pyrido[3,4-c]...)
Affinity DataKi:  3.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720189(6-({1-[6-(difluoromethyl)pyridin-3-yl]-4-methyl-1H...)
Affinity DataKi:  3.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720160(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4...)
Affinity DataKi:  3.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720162(2-methyl-6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2...)
Affinity DataKi:  4.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720163(2-cyclobutyl-6-{[5-methyl-3-(6-methylpyridin-3-yl)...)
Affinity DataKi:  4.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720169(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4...)
Affinity DataKi:  4.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720168(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4...)
Affinity DataKi:  4.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720175(2-methyl-5-{5-methyl-4-[({7-methyl-5H,6H,7H,8H-pyr...)
Affinity DataKi:  5.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720187(6-({1-[6-(difluoromethyl)pyridin-3-yl]-4-methyl-1H...)
Affinity DataKi:  5.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720172(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4...)
Affinity DataKi:  6.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720182(6-({1-[6-(difluoromethyl)pyridin-3-yl]-4-methyl-1H...)
Affinity DataKi:  7.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720170(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4...)
Affinity DataKi:  7.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720164(2-(cyclobutylmethyl)-6-{[5-methyl-3-(6-methylpyrid...)
Affinity DataKi:  7.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720183(6-({1-[6-(difluoromethyl)pyridin-3-yl]-4-methyl-1H...)
Affinity DataKi:  8.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720165(2-cyclopentyl-6-{[5-methyl-3-(6-methylpyridin-3-yl...)
Affinity DataKi:  8.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720167(6-({5-methyl-3-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  11.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720177(5-[5-methyl-4-({[7-(oxolan-3-yl)-5H,6H,7H,8H-pyrid...)
Affinity DataKi:  12.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720174(5-[5-methyl-4-({5H,6H,7H,8H-pyrido[3,4-c]pyridazin...)
Affinity DataKi:  17.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720176(5-[5-methyl-4-({5H,6H,7H,8H-pyrido[3,4-c]pyridazin...)
Affinity DataKi:  17.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720202(2-(3-ethyloxetan-3-yl)-6-{[4-methyl-1-(6-methylpyr...)
Affinity DataKi:  19nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720197(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  20.9nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720198(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  21.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720181(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  22.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720180(2-methyl-6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-...)
Affinity DataKi:  23nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720179(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  26.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720201(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  28nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720171(2-(1-methanesulfonylpropan-2-yl)-6-({5-methyl-3-[6...)
Affinity DataKi:  28.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720199(6-{[1-(6-methoxypyridin-3-yl)-4-methyl-1H-1,2,3-tr...)
Affinity DataKi:  28.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720166(6-({5-methyl-3-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  29.3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720192(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  29.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720188(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  29.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720178(3-{[3-({5-methyl-3-[6-(trifluoromethyl)pyridin-3-y...)
Affinity DataKi:  35.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720190(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  36nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720161(6-({5-methyl-3-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  37nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720196(6-({4-methyl-1-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  37.9nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720203(2-methyl-5-[4-methyl-5-({5H,6H,7H,8H-pyrido[3,4-c]...)
Affinity DataKi:  40.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720191(6-({4-methyl-1-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  44.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720193(6-{[1-(6-methoxypyridin-3-yl)-4-methyl-1H-1,2,3-tr...)
Affinity DataKi:  51.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720195(3-{[6-({4-methyl-1-[6-(trifluoromethyl)pyridin-3-y...)
Affinity DataKi:  53.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720200(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  61.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720205(5-{5-[({7-cyclobutyl-5H,6H,7H,8H-pyrido[3,4-c]pyri...)
Affinity DataKi:  61.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720186(2-methyl-6-({4-methyl-1-[6-(trifluoromethyl)pyridi...)
Affinity DataKi:  63.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720194(6-({4-methyl-1-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  88.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720185(6-({4-methyl-1-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  93.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720204(5-[5-({[7-(cyclobutylmethyl)-5H,6H,7H,8H-pyrido[3,...)
Affinity DataKi:  99.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandPNGBDBM720184(6-({4-methyl-1-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  128nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent