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Found
33
Enz. Inhib. hit(s) with all data for entry = 12557
Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708889
(2-(1-methyl-10-oxo-4-(1- (pyridin-2-ylmethyl)azeti...)
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Affinity Data
IC50: 4.60E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708903
(2-(9-oxo-2-(3-phenylpropan- oyl)-7-oxa-2,10-diazas...)
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Affinity Data
IC50: 8.20E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
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Ligand Info
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PC sid
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708892
(2-(4-(acetyl-D-prolyl)-1- methyl-10-oxo-1,4,9- tri...)
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Affinity Data
IC50: 1.25E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708883
(2-(4-(2-(4-hydroxyphen- yl)propanoyl)-1-methyl- 10...)
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Affinity Data
IC50: 1.98E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
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PC sid
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708897
(US20240425519, Compound AC0978)
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Affinity Data
IC50: 2.21E+4nM
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Target Info
PDB
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708872
(2-(1-methyl-10-oxo-4-(2- phenylcyclopropane-1- car...)
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Affinity Data
IC50: 3.20E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
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PC sid
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708880
(2-(1-methyl-10-oxo-4- (phenylcarbamoyl)-1,4,9- tri...)
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Affinity Data
IC50: 3.36E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
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Ligand Info
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PC sid
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708899
(2-(9-oxo-2-((R)-2-phenylpro- panoyl)-7-oxa-2,10-di...)
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Affinity Data
IC50: 3.96E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
In Depth
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708900
(2-(2-(cyclopentanecarbonyl)- 9-oxo-7-oxa-2,10-diaz...)
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Affinity Data
IC50: 4.01E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708891
(2-(4-(benzoyl-D-prolyl)- 1-methyl-10-oxo-1,4,9- tr...)
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Affinity Data
IC50: 4.54E+4nM
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Target Info
PDB
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Ligand Info
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PC sid
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708881
(2-(4-(benzylcarbamoyl)- 1-methyl-10-oxo-1,4,9- tri...)
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Affinity Data
IC50: 4.59E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
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Ligand Info
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PC sid
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Details
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708902
(2-(2-(2-(3-hydroxypyrrolidin- 1-yl)pyrimidin-4-yl)...)
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Affinity Data
IC50: 4.75E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
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Ligand Info
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PC sid
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708896
(2-(9-oxo-2-(2-phenylpropano- yl)-7-oxa-2,10-diazas...)
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Affinity Data
IC50: 5.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
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GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708901
(2-(2-(cyclobutanecarbonyl)-9- oxo-7-oxa-2,10-diaza...)
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Affinity Data
IC50: 5.10E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
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Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708873
(2-(1-methyl-4-(2-methyl- 3-phenylpropanoyl)-10- ox...)
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Affinity Data
IC50: 5.64E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
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PC sid
In Depth
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708898
(US20240425519, Compound AC0979)
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Affinity Data
IC50: 6.37E+4nM
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Target Info
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708887
(2-(4-(1-benzyl-5-oxo- pyrrolidine-3-carbonyl)- 1-m...)
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Affinity Data
IC50: 6.59E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
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Ligand Info
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PC sid
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708879
(2-(4-(cyclobutylcarbam- oyl)-1-methyl-10-oxo- 1,4,...)
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Affinity Data
IC50: 9.17E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
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Ligand Info
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PC sid
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708882
(2-(4-(cyclopropanecar- bonyl)-1-methyl-10-oxo- 1,4...)
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Affinity Data
IC50: 1.00E+5nM
More data for this Ligand-Target Pair
Target Info
PDB
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Ligand Info
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PC sid
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708878
(2-(4-(1-hydroxycyclopen- tane-1-carbonyl)-1-meth- ...)
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Affinity Data
IC50: 1.16E+5nM
More data for this Ligand-Target Pair
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708895
(2-(9-(carboxymethyl)-1-meth- yl-10-oxo-1,4,9-triaz...)
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Affinity Data
IC50: 1.23E+5nM
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708884
(2-(4-(2-methoxy-2-phen- ylpropanoyl)-1-methyl- 10-...)
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Affinity Data
IC50: 1.31E+5nM
More data for this Ligand-Target Pair
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708885
(2-(1-methyl-10-oxo-4-(1- phenyl-1H-pyrazole-4- car...)
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Affinity Data
IC50: 1.48E+5nM
More data for this Ligand-Target Pair
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PC sid
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708888
(2-(4-(1-acetylpiperidine- 4-carbonyl)-1-methyl-10-...)
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Affinity Data
IC50: 1.91E+5nM
More data for this Ligand-Target Pair
Target Info
PDB
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PC sid
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708890
(2-(4-(1-benzoylazetidine- 3-carbonyl)-1-methyl-10-...)
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Affinity Data
IC50: 1.99E+5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
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PC sid
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Details
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708876
(2-(1-methyl-4-(2-methyl- 2-phenoxypropanoyl)-10- o...)
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Affinity Data
IC50: 2.02E+5nM
More data for this Ligand-Target Pair
Target Info
PDB
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PC sid
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708874
(2-(4-(3,3-difluorocyclo- butane-1-carbonyl)-1- met...)
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Affinity Data
IC50: 2.95E+5nM
More data for this Ligand-Target Pair
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708875
(2-(4-(1-(4-fluorophenyl)- cyclopropane-1-carbon- y...)
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Affinity Data
IC50: 3.48E+5nM
More data for this Ligand-Target Pair
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PDB
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PC sid
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708894
(2-(4-(2-amino-5-chloro-6- methylpyrimidin-4-yl)-1-...)
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Affinity Data
IC50: 3.89E+5nM
More data for this Ligand-Target Pair
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708893
(2-(4-(6-acetyl-5,6,7,8-tetra- hydropyrido[4,3-d]py...)
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Affinity Data
IC50: 4.45E+5nM
More data for this Ligand-Target Pair
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708877
(2-(4-((1,3-trans)-3-((tert- butoxycarbonyl)amino)-...)
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Affinity Data
IC50: 4.93E+5nM
More data for this Ligand-Target Pair
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708886
(2-(4-((S)-1-(tert-butoxy- carbonyl)azetidine-2- ca...)
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Affinity Data
IC50: 4.96E+5nM
More data for this Ligand-Target Pair
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Target
Kelch domain-containing protein 2
(Human)
TBA
Ligand
BDBM708904
(2-(2-(2-methylpyrimidin-4-yl)- 9-oxo-7-oxa-2,10-di...)
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Affinity Data
IC50: 1.39E+6nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
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In Depth
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