Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 12488
TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 2(2-Fluoroethyl 2-{[6-(cyclopropylmethoxy)-5-(3-meth...)
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
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TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 1(Fluoromethyl 2-{[6-(cyclopropylmethoxy)-5-(3-metho...)
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 8(Fluoromethyl 2-{[6-(cyclopropylmethoxy)-5-(pyrroli...)
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 9(2-Fluoroethyl 2-{[6-(cyclopropylmethoxy)-5-(pyrrol...)
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 7(3-Fluoropropyl 2-{[6-(cyclopropylmethoxy)-5-(pyrro...)
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 3(3-Fluoropropyl 2-{[6-(cyclopropylmethoxy)-5-(3-met...)
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 4(Fluoromethyl 2-{[6-(cyclopropylmethoxy)-5-(3,3-dif...)
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 5(2-Fluoroethyl 2-{[6-(cyclopropylmethoxy)-5-(3,3-di...)
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 16(6-(Cyclopropylmethoxy)-N-[(2S)-1-(fluoromethoxy)-4...)
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 17(6-(Cyclopropylmethoxy)-N-[(2S)-1-(2-fluoroethoxy)-...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 25(6-(Cyclopropylmethoxy)-N-[(2S)-1-(fluoromethoxy)-4...)
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 14(2-Fluoroethyl N-[6-(cyclopropylmethoxy)-5-(pyrroli...)
Affinity DataKi:  15nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 11(2-Fluoroethyl N-[6-(cyclopropylmethoxy)-5-(3-metho...)
Affinity DataKi:  15nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 27(6-(Cyclopropylmethoxy)-N-[(2S)-1-(2-fluoroethoxy)-...)
Affinity DataKi:  18nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 6(3-Fluoropropyl 2-{[6-(cyclopropylmethoxy)-5-(3,3-d...)
Affinity DataKi:  19nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 26(6-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-y...)
Affinity DataKi:  24nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 28(6-(Cyclopropylmethoxy)-N-[(2S)-1-(3-fluoropropoxy)...)
Affinity DataKi:  31nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 34(6-(Cyclopropylmethoxy)-N-{3-[(fluoromethoxy)methyl...)
Affinity DataKi:  33nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 15(3-Fluoropropyl N-[6-(cyclopropylmethoxy)-5-(pyrrol...)
Affinity DataKi:  40nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 18(6-(Cyclopropylmethoxy)-N-[(2S)-1-(3-fluoropropoxy)...)
Affinity DataKi:  40nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 12(3-Fluoropropyl N-[6-(cyclopropylmethoxy)-5-(3-meth...)
Affinity DataKi:  46nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 20(6-(Cyclopropylmethoxy)-N-[(2S)-1-(2-fluoroethoxy)-...)
Affinity DataKi:  60nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 35(6-(Cyclopropylmethoxy)-N-{3-[(2-fluoroethoxy)methy...)
Affinity DataKi:  62nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 13(Fluoromethyl N-[6-(cyclopropylmethoxy)-5-(pyrrolid...)
Affinity DataKi:  63nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 36(6-(Cyclopropylmethoxy)-N-{3-[(3-fluoropropoxy)meth...)
Affinity DataKi:  68nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 19(6-(Cylopropylmethoxy)-N-[(2S)-1-(fluoromethoxy)-3-...)
Affinity DataKi:  70nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 21(6-(Cyclopropylmethoxy)-N-[(2S)-1-(3-fluoropropoxy)...)
Affinity DataKi:  156nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 30(6-(Cyclopropylmethoxy)-N-[(2S)-1-(2-fluoroethoxy)-...)
Affinity DataKi:  165nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 31(6-(Cyclopropylmethoxy)-N-[(2S)-1-(3-fluoropropoxy)...)
Affinity DataKi:  247nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 29(6-(Cyclopropylmethoxy)-N-[(2S)-1-(fluoromethoxy)-3...)
Affinity DataKi:  269nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 37(6-(Cyclopropylmethoxy)-N-[(2R)-1-(2-fluoroethoxy)-...)
Affinity DataKi:  288nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 10(Fluoromethyl N-[6-(cyclopropylmethoxy)-5-(3-methox...)
Affinity DataKi:  336nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 23(6-(Cyclopropylmethoxy)-N-[(2S)-1-(2-fluoroethoxy)p...)
Affinity DataKi:  490nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM706180(6-(Cyclopropylmethoxy)-5-(3-fluoro-3-methylazetidi...)
Affinity DataKi:  524nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 24(6-(Cyclopropylmethoxy)-N-[(2S)-1-(3-fluoropropoxy)...)
Affinity DataKi:  671nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 22(6-(Cyclopropylmethoxy)-N-[(2S)-1-(fluoromethoxy)pr...)
Affinity DataKi:  787nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 38(6-(Cyclopropylmethoxy)-N-[(2R)-1-(2-fluoroethoxy)-...)
Affinity DataKi:  1.30E+3nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 33(6-(Cyclopropylmethoxy)-N-[(2S)-1-(3-fluoropropoxy)...)
Affinity DataKi:  2.81E+3nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGUS20240383872, Example 32(6-(Cyclopropylmethoxy)-N-[(2S)-1-(2-fluoroethoxy)p...)
Affinity DataKi:  3.12E+3nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent