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Found
63
Enz. Inhib. hit(s) with all data for entry = 12457
Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704081
(N-(3-(difluoromethyl)-1-((1R,4S)-4-((9-(3-(2,4-dio...)
Copy SMILES
Affinity Data
IC50: 2.98nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704071
(N-(3-(difluoromethyl)-1-((1R,4S)-4-(((2-(1-(3-(2,4...)
Copy SMILES
Affinity Data
IC50: 3.36nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704055
(N-(1-(1-((3-(4-chloro-3-(2,4-dioxotetrahydropyrimi...)
Copy SMILES
Affinity Data
IC50: 3.80nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
Copy reaction URL
Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704072
(5-((S)-3-aminopiperidin-1-yl)-N-(3-(difluoromethyl...)
Copy SMILES
Affinity Data
IC50: 3.86nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704091
(US20240368194, Example 56)
Copy SMILES
Affinity Data
IC50: 3.87nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704092
(US20240368194, Example 57)
Copy SMILES
Affinity Data
IC50: 4.57nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Copy BDB DOI
Copy reaction URL
Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704066
(N-(1-((1R,4R)-4-(((2-(1-(4-chloro-3-(2,4-dioxotetr...)
Copy SMILES
Affinity Data
IC50: 4.64nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704098
((S)-5-(3-aminopiperidin-1-yl)-N-(1-(1-((3-(4-chlor...)
Copy SMILES
Affinity Data
IC50: 5.93nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704060
(US20240368194, Example 24)
Copy SMILES
Affinity Data
IC50: 6.08nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704085
((S)-5-(3-aminopiperidin-1-yl)-N-(3-(difluoromethyl...)
Copy SMILES
Affinity Data
IC50: 7.05nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704068
(5-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-N-(1-((1R,...)
Copy SMILES
Affinity Data
IC50: 7.74nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704083
(5-((S)-3-aminopiperidin-1-yl)-N-(1-((1R,4S)-4-(((2...)
Copy SMILES
Affinity Data
IC50: 7.86nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704067
(5-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-N-(1-(((1R...)
Copy SMILES
Affinity Data
IC50: 8.05nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
Copy reaction URL
Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704093
(N-(3-(difluoromethyl)-1-((1R,4R)-4-(((3-(3-(2,4-di...)
Copy SMILES
Affinity Data
IC50: 8.71nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704052
(5-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-N-(3-(difl...)
Copy SMILES
Affinity Data
IC50: 8.80nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704095
(N-(3-(difluoromethyl)-1-(1-(4-(9-(3-(2,4-dioxotetr...)
Copy SMILES
Affinity Data
IC50: 9.06nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704058
(N-(2-((1S,4S)-4-((2-(1-(4-chloro-3-(2,4-dioxotetra...)
Copy SMILES
Affinity Data
IC50: 9.29nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704089
(N-(3-(difluoromethyl)-1-((1R,4R)-4-((2-(1-(3-(2,6-...)
Copy SMILES
Affinity Data
IC50: 9.82nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704057
(5-((1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)-N...)
Copy SMILES
Affinity Data
IC50: 9.90nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704044
(N-(2-((1S,4S)-4-(((1-(4-chloro-3-(2,4-dioxotetrahy...)
Copy SMILES
Affinity Data
IC50: 10.6nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704070
(US20240368194, Example 34)
Copy SMILES
Affinity Data
IC50: 11nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704046
(N-(2-((1S,4S)-4-((2-(1-(4-chloro-3-(2,4-dioxotetra...)
Copy SMILES
Affinity Data
IC50: 12.9nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704064
(US20240368194, Example 28)
Copy SMILES
Affinity Data
IC50: 12.9nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
Copy reaction URL
Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704073
(N-(3-(difluoromethyl)-1-(1-(2-(1-(3-(2,4-dioxotetr...)
Copy SMILES
Affinity Data
IC50: 13.1nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
Copy reaction URL
Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704080
(5-((1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)-N...)
Copy SMILES
Affinity Data
IC50: 13.4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704063
(US20240368194, Example 27)
Copy SMILES
Affinity Data
IC50: 13.5nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
Copy reaction URL
Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704061
(US20240368194, Example 25)
Copy SMILES
Affinity Data
IC50: 14.1nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
Copy reaction URL
Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704051
(N-(1-(1-((3-(4-chloro-3-(2,4-dioxotetrahydropyrimi...)
Copy SMILES
Affinity Data
IC50: 14.2nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704062
(US20240368194, Example 26)
Copy SMILES
Affinity Data
IC50: 14.3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
Copy reaction URL
Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704053
(N-(2-((1S,4S)-4-((((3-(4-chloro-3-(2,4-dioxotetrah...)
Copy SMILES
Affinity Data
IC50: 15.1nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704038
(US20240368194, Example 2)
Copy SMILES
Affinity Data
IC50: 15.5nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704065
(N-(1-((1R,4R)-4-((9-(4-chloro-3-(2,4-dioxotetrahyd...)
Copy SMILES
Affinity Data
IC50: 17nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704075
(N-(3-(difluoromethyl)-1-((1R,4R)-4-(((2-(1-(3-(2,4...)
Copy SMILES
Affinity Data
IC50: 17nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704047
(5-((1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)-N...)
Copy SMILES
Affinity Data
IC50: 18.5nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704078
(US20240368194, Example 42)
Copy SMILES
Affinity Data
IC50: 18.6nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704049
(US20240368194, Example 13)
Copy SMILES
Affinity Data
IC50: 19.3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704074
(N(1-((1R,4R)-4-((4-((3-(4-chloro-3-(2,4-dioxotetra...)
Copy SMILES
Affinity Data
IC50: 20nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704090
(US20240368194, Example 55)
Copy SMILES
Affinity Data
IC50: 21.3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704094
(N-(3-(difluoromethyl)-1-(1-(3-(9-(3-(2,4-dioxotetr...)
Copy SMILES
Affinity Data
IC50: 21.9nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
Copy reaction URL
Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704059
(5-((1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)-N...)
Copy SMILES
Affinity Data
IC50: 23nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
Copy reaction URL
Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704088
(US20240368194, Example 52)
Copy SMILES
Affinity Data
IC50: 23.8nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704069
(US20240368194, Example 33)
Copy SMILES
Affinity Data
IC50: 23.9nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704077
(N-(3-(difluoromethyl)-1-((1R,4R)-4-(((2-(1-(3-(2,4...)
Copy SMILES
Affinity Data
IC50: 25.5nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704087
(5-((1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)-N...)
Copy SMILES
Affinity Data
IC50: 27.1nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704096
(N-(3-(difluoromethyl)-1-(1-(4-(4-(3-(2,6-dioxopipe...)
Copy SMILES
Affinity Data
IC50: 28.9nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704037
(US20240368194, Example 1)
Copy SMILES
Affinity Data
IC50: 30.3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704076
(5-((1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)-N...)
Copy SMILES
Affinity Data
IC50: 34.5nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704084
(N-(1-((1R,4R)-4-((9-(4-chloro-3-(2,4-dioxotetrahyd...)
Copy SMILES
Affinity Data
IC50: 36.1nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704097
(US20240368194, Example 63)
Copy SMILES
Affinity Data
IC50: 36.2nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
Copy reaction URL
Target
Interleukin-1 receptor-associated kinase 4
(Human)
TBA
Ligand
BDBM704086
(N-(3-(difluoromethyl)-1-(1-((3-(3-(2,4-dioxotetrah...)
Copy SMILES
Affinity Data
IC50: 36.7nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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