Compile Data Set for Download or QSAR
Report error Found 93 Enz. Inhib. hit(s) with all data for entry = 12375
TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM50584228(CHEMBL4597954 | US20240327418, Comparative example...)
Affinity DataIC50: 0.280nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM50584230(CHEMBL5083249 | US20240327418, Example LEE15)
Affinity DataIC50: 0.383nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM50584229(CHEMBL5078985 | US20240327418, Example LEE16)
Affinity DataIC50: 0.435nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699116(US20240327418, Example LEE20)
Affinity DataIC50: 0.520nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM50584227(CHEMBL5087431 | US20240327418, Example LEE17)
Affinity DataIC50: 0.551nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699115(US20240327418, Example LEE18)
Affinity DataIC50: 0.710nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM476626(N-(4-(2-propylhydrazine-1- carbonyl)benzyl)cinnama...)
Affinity DataIC50: 0.950nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699131(US20240327418, Example LEE41)
Affinity DataIC50: 1.08nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699120(US20240327418, Example LEE19)
Affinity DataIC50: 1.20nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699110(US20240327418, Example LEE13)
Affinity DataIC50: 1.82nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699124(US20240327418, Example LEE37)
Affinity DataIC50: 1.98nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699122(US20240327418, Example LEE21)
Affinity DataIC50: 2.42nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699111(US20240327418, Example LEE14)
Affinity DataIC50: 2.74nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699121(US20240327418, Example LEE7)
Affinity DataIC50: 2.97nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM50584229(CHEMBL5078985 | US20240327418, Example LEE16)
Affinity DataIC50: 3.01nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699109(US20240327418, Example LEE12)
Affinity DataIC50: 3.12nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM50584230(CHEMBL5083249 | US20240327418, Example LEE15)
Affinity DataIC50: 3.52nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM50584227(CHEMBL5087431 | US20240327418, Example LEE17)
Affinity DataIC50: 3.79nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM50584228(CHEMBL4597954 | US20240327418, Comparative example...)
Affinity DataIC50: 5.17nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699132(US20240327418, Example LEE10)
Affinity DataIC50: 5.43nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699115(US20240327418, Example LEE18)
Affinity DataIC50: 7.61nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699122(US20240327418, Example LEE21)
Affinity DataIC50: 8.17nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699130(US20240327418, Example LEE11)
Affinity DataIC50: 8.78nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699120(US20240327418, Example LEE19)
Affinity DataIC50: 10.1nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699116(US20240327418, Example LEE20)
Affinity DataIC50: 10.3nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM476626(N-(4-(2-propylhydrazine-1- carbonyl)benzyl)cinnama...)
Affinity DataIC50: 11.8nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699127(US20240327418, Example LEE40)
Affinity DataIC50: 12.4nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699111(US20240327418, Example LEE14)
Affinity DataIC50: 12.7nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699110(US20240327418, Example LEE13)
Affinity DataIC50: 13.2nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 2(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM50584230(CHEMBL5083249 | US20240327418, Example LEE15)
Affinity DataIC50: 15.1nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 2(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM50584227(CHEMBL5087431 | US20240327418, Example LEE17)
Affinity DataIC50: 16.9nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699124(US20240327418, Example LEE37)
Affinity DataIC50: 17.8nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699131(US20240327418, Example LEE41)
Affinity DataIC50: 18nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 2(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM50584229(CHEMBL5078985 | US20240327418, Example LEE16)
Affinity DataIC50: 18.5nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699114(US20240327418, Example LEE3)
Affinity DataIC50: 20.1nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699109(US20240327418, Example LEE12)
Affinity DataIC50: 25.1nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699121(US20240327418, Example LEE7)
Affinity DataIC50: 25.1nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699125(US20240327418, Example LEE8)
Affinity DataIC50: 26.4nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 2(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699115(US20240327418, Example LEE18)
Affinity DataIC50: 37.8nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 2(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699116(US20240327418, Example LEE20)
Affinity DataIC50: 38.4nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 43.8nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetHistone deacetylase 2(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699110(US20240327418, Example LEE13)
Affinity DataIC50: 49.2nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 2(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM50584228(CHEMBL4597954 | US20240327418, Comparative example...)
Affinity DataIC50: 49.5nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 2(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699122(US20240327418, Example LEE21)
Affinity DataIC50: 51.5nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699127(US20240327418, Example LEE40)
Affinity DataIC50: 53.9nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 53.9nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699130(US20240327418, Example LEE11)
Affinity DataIC50: 56.1nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699132(US20240327418, Example LEE10)
Affinity DataIC50: 57.4nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 2(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699120(US20240327418, Example LEE19)
Affinity DataIC50: 60nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
OCEAN UNIVERSITY OF CHINA; QINGDAO HIGENE BIOPHARMACEUTICAL CO., LTD; MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD

US Patent
LigandPNGBDBM699129(US20240327418, Example LEE4)
Affinity DataIC50: 76.7nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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