Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 12345
TargetSteroid hormone receptor ERR1(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696507(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50:  191nMAssay Description:The binding activity of the compound to ER was determined using the LanthaScreen TR-FRET ER Alpha Coactivator Assay kit (brand: Thermo, Cat. No: A158...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
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TargetProgesterone receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696514(Synthesis of (2S,6aS,6bR,7S,8aS,8bS,10R,11aR,12aS,...)
Affinity DataEC50: >3.00E+4nMAssay Description:The binding activity of the compound to PR was determined using the LanthaScreen TR-FRET Progesterone Receptor Coactivator Assay kit (brand: Thermo, ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
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TargetAndrogen receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696514(Synthesis of (2S,6aS,6bR,7S,8aS,8bS,10R,11aR,12aS,...)
Affinity DataEC50: >3.00E+4nMAssay Description:The binding activity of the compound to AR was determined using the LanthaScreen TR-FRET Androgen Receptor Coactivator Assay kit (brand: Thermo, Cat....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetSteroid hormone receptor ERR1(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696514(Synthesis of (2S,6aS,6bR,7S,8aS,8bS,10R,11aR,12aS,...)
Affinity DataEC50:  52nMAssay Description:The binding activity of the compound to ER was determined using the LanthaScreen TR-FRET ER Alpha Coactivator Assay kit (brand: Thermo, Cat. No: A158...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetGlucocorticoid receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696514(Synthesis of (2S,6aS,6bR,7S,8aS,8bS,10R,11aR,12aS,...)
Affinity DataEC50:  16.4nMAssay Description:The binding activity of the compound to GR was determined using the Polarscreen Glucocorticoid Receptor Assay Kit, Red (brand: Thermo, Cat. No: A1589...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetProgesterone receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696513(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50: >3.00E+4nMAssay Description:The binding activity of the compound to PR was determined using the LanthaScreen TR-FRET Progesterone Receptor Coactivator Assay kit (brand: Thermo, ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetAndrogen receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696513(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50: >3.00E+4nMAssay Description:The binding activity of the compound to AR was determined using the LanthaScreen TR-FRET Androgen Receptor Coactivator Assay kit (brand: Thermo, Cat....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetSteroid hormone receptor ERR1(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696513(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50:  427nMAssay Description:The binding activity of the compound to ER was determined using the LanthaScreen TR-FRET ER Alpha Coactivator Assay kit (brand: Thermo, Cat. No: A158...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetGlucocorticoid receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696513(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50:  20.2nMAssay Description:The binding activity of the compound to GR was determined using the Polarscreen Glucocorticoid Receptor Assay Kit, Red (brand: Thermo, Cat. No: A1589...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetGlucocorticoid receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696512(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50:  17.1nMAssay Description:The binding activity of the compound to GR was determined using the Polarscreen Glucocorticoid Receptor Assay Kit, Red (brand: Thermo, Cat. No: A1589...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetProgesterone receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696511(Synthesis of (2S,6aS,6bR,7S,8aS,8bS,10R,11aR,12aS,...)
Affinity DataEC50: >3.00E+4nMAssay Description:The binding activity of the compound to PR was determined using the LanthaScreen TR-FRET Progesterone Receptor Coactivator Assay kit (brand: Thermo, ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetAndrogen receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696511(Synthesis of (2S,6aS,6bR,7S,8aS,8bS,10R,11aR,12aS,...)
Affinity DataEC50: >3.00E+4nMAssay Description:The binding activity of the compound to AR was determined using the LanthaScreen TR-FRET Androgen Receptor Coactivator Assay kit (brand: Thermo, Cat....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetSteroid hormone receptor ERR1(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696511(Synthesis of (2S,6aS,6bR,7S,8aS,8bS,10R,11aR,12aS,...)
Affinity DataEC50:  111nMAssay Description:The binding activity of the compound to ER was determined using the LanthaScreen TR-FRET ER Alpha Coactivator Assay kit (brand: Thermo, Cat. No: A158...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetGlucocorticoid receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696511(Synthesis of (2S,6aS,6bR,7S,8aS,8bS,10R,11aR,12aS,...)
Affinity DataEC50:  42.3nMAssay Description:The binding activity of the compound to GR was determined using the Polarscreen Glucocorticoid Receptor Assay Kit, Red (brand: Thermo, Cat. No: A1589...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetGlucocorticoid receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696510(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50:  42.5nMAssay Description:The binding activity of the compound to GR was determined using the Polarscreen Glucocorticoid Receptor Assay Kit, Red (brand: Thermo, Cat. No: A1589...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetProgesterone receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696509(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50: >3.00E+4nMAssay Description:The binding activity of the compound to PR was determined using the LanthaScreen TR-FRET Progesterone Receptor Coactivator Assay kit (brand: Thermo, ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetAndrogen receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696509(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50: >3.00E+4nMAssay Description:The binding activity of the compound to AR was determined using the LanthaScreen TR-FRET Androgen Receptor Coactivator Assay kit (brand: Thermo, Cat....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetSteroid hormone receptor ERR1(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696509(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50:  490nMAssay Description:The binding activity of the compound to ER was determined using the LanthaScreen TR-FRET ER Alpha Coactivator Assay kit (brand: Thermo, Cat. No: A158...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetGlucocorticoid receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696509(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50:  121nMAssay Description:The binding activity of the compound to GR was determined using the Polarscreen Glucocorticoid Receptor Assay Kit, Red (brand: Thermo, Cat. No: A1589...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetProgesterone receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696507(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50: >3.00E+4nMAssay Description:The binding activity of the compound to PR was determined using the LanthaScreen TR-FRET Progesterone Receptor Coactivator Assay kit (brand: Thermo, ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetAndrogen receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696507(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50: >3.00E+4nMAssay Description:The binding activity of the compound to AR was determined using the LanthaScreen TR-FRET Androgen Receptor Coactivator Assay kit (brand: Thermo, Cat....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetGlucocorticoid receptor(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696507(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataEC50:  13nMAssay Description:The binding activity of the compound to GR was determined using the Polarscreen Glucocorticoid Receptor Assay Kit, Red (brand: Thermo, Cat. No: A1589...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696513(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataIC50: 7.20E+3nMAssay Description:I. Experimental Materials and Instruments1. Human liver microsome (Corning 452117)2. NADPH (Solarbio 705Y021)3. Positive substrates diclofenac (Sigma...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Jiangsu Simcere Pharmaceutical

US Patent
LigandPNGBDBM696513(Synthesis of (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12b...)
Affinity DataIC50: 5.00E+4nMAssay Description:I. Experimental Materials and Instruments1. Human liver microsome (Corning 452117)2. NADPH (Solarbio 705Y021)3. Positive substrates diclofenac (Sigma...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent