Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 12296
TargetPoly [ADP-ribose] polymerase 1(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandPNGBDBM595711(US11591331, Example 22A | US20240287094, Example 2)
Affinity DataIC50: 11nMAssay Description:In vitro binding activities for PARP1 and PARP2 were tested by the following method.I. Materials and instruments1. PARP1 recombinant protein (Sino Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandPNGBDBM694225(US20240287094, Example 8 | (R)-3-((7-Ethyl-6-oxo-5...)
Affinity DataIC50: 19nMAssay Description:In vitro binding activities for PARP1 and PARP2 were tested by the following method.I. Materials and instruments1. PARP1 recombinant protein (Sino Bi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandPNGBDBM595711(US11591331, Example 22A | US20240287094, Example 2)
Affinity DataIC50: 1.78E+3nMAssay Description:In vitro binding activities for PARP1 and PARP2 were tested by the following method.I. Materials and instruments1. PARP1 recombinant protein (Sino Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandPNGBDBM694225(US20240287094, Example 8 | (R)-3-((7-Ethyl-6-oxo-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro binding activities for PARP1 and PARP2 were tested by the following method.I. Materials and instruments1. PARP1 recombinant protein (Sino Bi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent