Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 12279
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693110(US20240270753, Compound ZB-S-84)
Affinity DataIC50: 4.10nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693125(US20240270753, Compound ZB-S-104)
Affinity DataIC50: 4.10nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693127(US20240270753, Compound ZB-S-106)
Affinity DataIC50: 4.30nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693126(US20240270753, Compound ZB-S-105)
Affinity DataIC50: 4.70nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693111(US20240270753, Compound ZB-S-85)
Affinity DataIC50: 5.5nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693113(US20240270753, Compound ZB-S-87)
Affinity DataIC50: 5.80nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693124(US20240270753, Compound ZB-S-103)
Affinity DataIC50: 7.10nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693109(US20240270753, Compound ZB-S-83)
Affinity DataIC50: 7.20nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50553783(Ptpn11 inhibitor tno155 | Shp2 inhibitor tno155 | ...)
Affinity DataIC50: 9nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693112(US20240270753, Compound ZB-S-86)
Affinity DataIC50: 9.80nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693108(US20240270753, Compound ZB-S-82)
Affinity DataIC50: 9.80nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693118(US20240270753, Compound ZB-S-92)
Affinity DataIC50: 10nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693114(US20240270753, Compound ZB-S-88)
Affinity DataIC50: 10.8nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693120(US20240270753, Compound ZB-S-94)
Affinity DataIC50: 14.8nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693117(US20240270753, Compound ZB-S-91)
Affinity DataIC50: 15.4nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693119(US20240270753, Compound ZB-S-93)
Affinity DataIC50: 17.5nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693115(US20240270753, Compound ZB-S-89)
Affinity DataIC50: 20.7nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693123(US20240270753, Compound ZB-S-102)
Affinity DataIC50: 22.6nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693121(US20240270753, Compound ZB-S-100)
Affinity DataIC50: 23nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693122(US20240270753, Compound ZB-S-101)
Affinity DataIC50: 27.5nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM693116(US20240270753, Compound ZB-S-90)
Affinity DataIC50: 63.8nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataIC50: 155nMAssay Description:(a) The positive control SHP099 was prepared according to the reported literature (J Med Chem 2016, 59 (17), 7773-82); and the positive control TNO15...More data for this Ligand-Target Pair
In DepthDetails
US Patent