Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 12274
TargetMitogen-activated protein kinase 11(Human)
Prazertherapeutics

US Patent
LigandPNGBDBM682026(3-(5-(1H-indole-3- carbonyl)pyridin-2-yl)-N- cyclo...)
Affinity DataIC50: 18.8nMAssay Description:Briefly, the compounds were diluted at concentrations of 1000, 333, 111, 37.0, 12.3, 4.12, 1.37, 0.457, 0.152, and 0.0495 nM, respectively, and then ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
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TargetMitogen-activated protein kinase 11(Human)
Prazertherapeutics

US Patent
LigandPNGBDBM682023(N-Cyclopropyl-3-(5-(4-(2,3- dihydroxypropoxy)benzo...)
Affinity DataIC50: 22.3nMAssay Description:Briefly, the compounds were diluted at concentrations of 1000, 333, 111, 37.0, 12.3, 4.12, 1.37, 0.457, 0.152, and 0.0495 nM, respectively, and then ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
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TargetMitogen-activated protein kinase 11(Human)
Prazertherapeutics

US Patent
LigandPNGBDBM682024(6-Chloro-N-cyclopropyl-4'- (1H-indole-3-carbonyl)-...)
Affinity DataIC50: 34.1nMAssay Description:Briefly, the compounds were diluted at concentrations of 1000, 333, 111, 37.0, 12.3, 4.12, 1.37, 0.457, 0.152, and 0.0495 nM, respectively, and then ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 11(Human)
Prazertherapeutics

US Patent
LigandPNGBDBM682025(N-Cyclopropyl-3-(5-(6-(2,3- dihydroxypropoxy)-1H-i...)
Affinity DataIC50: 34.3nMAssay Description:Briefly, the compounds were diluted at concentrations of 1000, 333, 111, 37.0, 12.3, 4.12, 1.37, 0.457, 0.152, and 0.0495 nM, respectively, and then ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 11(Human)
Prazertherapeutics

US Patent
LigandPNGBDBM682027(3-(5-(1-Benzyl-1H-indole-3- carbonyl)pyridin-2-yl)...)
Affinity DataIC50: 193nMAssay Description:Briefly, the compounds were diluted at concentrations of 1000, 333, 111, 37.0, 12.3, 4.12, 1.37, 0.457, 0.152, and 0.0495 nM, respectively, and then ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent