Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 12236
TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689169(US20240254093, Example 16 | 3-((3-(6- (benzyloxy)p...)
Affinity DataKi:  0.0600nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
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Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689158(US20240254093, Example 5 | N-benzyl-3'-((2- hydrox...)
Affinity DataKi:  0.0800nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689168(US20240254093, Example 15 | 3-((5-(1H-tetrazol-5- ...)
Affinity DataKi:  0.160nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689165(US20240254093, Example 12 | 3'-((2-hydroxy-3,4- di...)
Affinity DataKi:  0.310nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689131(US20240254093, Example 3 | 3-((5-(1H-tetrazol-5- y...)
Affinity DataKi:  0.350nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689179(US20240254093, Example 26 | 3-((3-(6-(2-(3,5- bis(...)
Affinity DataKi:  0.360nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689172(US20240254093, Example 19 | 3-((3-(1H-tetrazol-5- ...)
Affinity DataKi:  0.360nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689178(US20240254093, Example 25 | 3-((3-(1H-indazol-5- y...)
Affinity DataKi:  0.370nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689176(US20240254093, Example 23 | 3-((3-(1H-tetrazol-5- ...)
Affinity DataKi:  0.460nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689162(US20240254093, Example 9 | 3-hydroxy-4-((3'- metho...)
Affinity DataKi:  0.460nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689129(US20240254093, Example 2 | 3-((3-(1H-tetrazol-5- y...)
Affinity DataKi:  0.480nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689167(US20240254093, Example 14 | 3-((4-chloro-3-(1H- te...)
Affinity DataKi:  0.600nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689182(US20240254093, Example 29 | 3-hydroxy-4-((3- (pyri...)
Affinity DataKi:  0.740nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689180(US20240254093, Example 27 | 3-((3-(1H-tetrazol-5- ...)
Affinity DataKi:  0.75nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689174(US20240254093, Example 21 | 3-((3-(2-benzyl-2H- in...)
Affinity DataKi:  0.910nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689166(US20240254093, Example 13 | 3-((4-fluoro-3-(1H- te...)
Affinity DataKi:  0.990nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689173(US20240254093, Example 20 | 3-((3-(1H-tetrazol-5- ...)
Affinity DataKi:  1.06nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689161(US20240254093, Example 8 | 3'-((2-hydroxy-3,4- dio...)
Affinity DataKi:  1.47nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689184(US20240254093, Example 31 | N-(4- carbamoylbenzyl)...)
Affinity DataKi:  1.61nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689159(US20240254093, Example 6 | N-benzyl-3'-((2- hydrox...)
Affinity DataKi:  1.82nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689171(US20240254093, Example 18 | 3-hydroxy-4-((6- pheny...)
Affinity DataKi:  2.65nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689163(US20240254093, Example 10 | 3-((3-ethyl-5-(1H- tet...)
Affinity DataKi:  2.75nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689160(US20240254093, Example 7 | 3'-((2-hydroxy-3,4- dio...)
Affinity DataKi:  2.77nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689175(US20240254093, Example 22 | 3-hydroxy-4-((6- pheno...)
Affinity DataKi:  3.66nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689157(US20240254093, Example 4 | ethyl 3'-((2-hydroxy- 3...)
Affinity DataKi:  3.83nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689183(US20240254093, Example 30 | 3'-((2-hydroxy-3,4- di...)
Affinity DataKi:  5.99nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689164(US20240254093, Example 11 | 3'-((2-hydroxy-3,4- di...)
Affinity DataKi:  6.24nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689170(US20240254093, Example 17 | 3-hydroxy-4-((6- metho...)
Affinity DataKi:  7.85nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689128(US20240254093, Example 1 | 3-((3-(1H-tetrazol-5- y...)
Affinity DataKi:  9.81nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689181(US20240254093, Example 28 | 3-((3-cyclohexyl-5- (1...)
Affinity DataKi:  12.5nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetG-protein coupled receptor 35(Human)
Heptares Therapeutics Limited

US Patent
LigandPNGBDBM689177(US20240254093, Example 24 | 3-((3-cyclopropyl-5- (...)
Affinity DataKi:  15.2nMAssay Description:Overexpression of Human GPR35a Baculovirus in HEK293f cells at a cell density of 2.5��106 cells/mL and a multiplicity of infection of 2.5 over 24 h i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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