Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 12131
LigandPNGBDBM629322(US20240025919, Compound 81 | US20230339981, Exampl...)
Affinity DataIC50: 0.230nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
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Date in BDB:
9/24/2024
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LigandPNGBDBM629373(US20230339981, Example 57 | US20240199644, Compoun...)
Affinity DataIC50: 0.452nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
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Date in BDB:
9/24/2024
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LigandPNGBDBM629344(US20230339981, Example 28 | US20240199644, Compoun...)
Affinity DataIC50: 0.659nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
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Date in BDB:
9/24/2024
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LigandPNGBDBM681816(US20240199644, Compound 13)
Affinity DataIC50: 0.691nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
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Date in BDB:
9/24/2024
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LigandPNGBDBM681817(US20240199644, Compound 14)
Affinity DataIC50: 1.15nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
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Date in BDB:
9/24/2024
Entry Details
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LigandPNGBDBM681808(US20240199644, Compound 5)
Affinity DataIC50: 1.16nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
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Date in BDB:
9/24/2024
Entry Details
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LigandPNGBDBM681807(US20240199644, Compound 4)
Affinity DataIC50: 2.5nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
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Date in BDB:
9/24/2024
Entry Details
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LigandPNGBDBM681814(US20240199644, Compound 11)
Affinity DataIC50: 7.24nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
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Date in BDB:
9/24/2024
Entry Details
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LigandPNGBDBM681818(US20240199644, Compound 15)
Affinity DataIC50: 11nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
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Date in BDB:
9/24/2024
Entry Details
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LigandPNGBDBM681811(US20240199644, Compound 8)
Affinity DataIC50: 32.6nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
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Date in BDB:
9/24/2024
Entry Details
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LigandPNGBDBM681815(US20240199644, Compound 12)
Affinity DataIC50: 35.8nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
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Date in BDB:
9/24/2024
Entry Details
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LigandPNGBDBM681812(US20240199644, Compound 9)
Affinity DataIC50: 81nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
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Date in BDB:
9/24/2024
Entry Details
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LigandPNGBDBM681819(US20240199644, Compound 16)
Affinity DataIC50: 86.1nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
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Date in BDB:
9/24/2024
Entry Details
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LigandPNGBDBM681806(US20240199644, Compound 3)
Affinity DataIC50: 294nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
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Date in BDB:
9/24/2024
Entry Details
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LigandPNGBDBM681805(US20240199644, Compound 2)
Affinity DataIC50: 880nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
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Date in BDB:
9/24/2024
Entry Details
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LigandPNGBDBM681804(US20240199644, Compound 1)
Affinity DataIC50: 3.86E+3nMAssay Description:GppNp-loaded HIS-KRAS(G12D, aa 1-169) was pre-incubated with a compound in the presence of 200 uM GTP in a 384-well plate (Greiner) for 15 min, then ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
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