Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 12226
TargetEnoyl-[acyl-carrier-protein] reductase [NADH]()
University of Illinois

US Patent
LigandPNGBDBM688743(US20240190872, Compound Fabimycin)
Affinity DataKi:  3nMAssay Description:To probe the effects of varying ring systems and amine placement on FabI target engagement, the apparent inhibition constants (Kiapp) for select comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
University of Illinois

US Patent
LigandPNGBDBM688741(US20240190872, Compound (+-)-Debio-1452-NH3 | (E)-...)
Affinity DataKi:  3.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
University of Illinois

US Patent
LigandPNGBDBM50052244(CHEMBL1652621 | US20240190872, Compound Debio-1452)
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetEnoyl-[acyl-carrier-protein] reductase [NADH]()
University of Illinois

US Patent
LigandPNGBDBM688742(US20240190872, Compound (R)-11)
Affinity DataKi:  89nMAssay Description:To probe the effects of varying ring systems and amine placement on FabI target engagement, the apparent inhibition constants (Kiapp) for select comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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PDB3D3D Structure (crystal)
TargetEnoyl-[acyl-carrier-protein] reductase [NADH]()
University of Illinois

US Patent
LigandPNGBDBM688741(US20240190872, Compound (+-)-Debio-1452-NH3 | (E)-...)
Affinity DataKi:  114nMAssay Description:To probe the effects of varying ring systems and amine placement on FabI target engagement, the apparent inhibition constants (Kiapp) for select comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetEnoyl-[acyl-carrier-protein] reductase [NADH]()
University of Illinois

US Patent
LigandPNGBDBM50052244(CHEMBL1652621 | US20240190872, Compound Debio-1452)
Affinity DataKi:  799nMAssay Description:To probe the effects of varying ring systems and amine placement on FabI target engagement, the apparent inhibition constants (Kiapp) for select comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent