Compile Data Set for Download or QSAR
Report error Found 222 Enz. Inhib. hit(s) with all data for entry = 12006
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669853(US20240132489, Compound 27 | (S)-4-(6-(3,6-dihydro...)
Affinity DataIC50: 2.17nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
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TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669874(US20240132489, Compound Mixture 105 and 106)
Affinity DataIC50: 2.70nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669878(US20240132489, Compound 110 | formate )
Affinity DataIC50: 3.48nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669855(US20240132489, Compound 29 | US20240132489, Compou...)
Affinity DataIC50: 4.36nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
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TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669880(US20240132489, Compound 113 | Monomer )
Affinity DataIC50: 4.76nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669877(US20240132489, Compound 109 | (S)-4-(6-(3,4-dihydr...)
Affinity DataIC50: 5.62nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669879(US20240132489, Compound 112 | Monomer )
Affinity DataIC50: 5.82nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669873(US20240132489, Compound 104 | formate )
Affinity DataIC50: 5.85nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669855(US20240132489, Compound 29 | US20240132489, Compou...)
Affinity DataIC50: 6.40nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669851(US20240132489, Compound 25 | (S)-4-(3-(2-(piperidi...)
Affinity DataIC50: 6.5nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669881(US20240132489, Compound 114 | formate )
Affinity DataIC50: 6.73nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669854(US20240132489, Compound 28 | formate )
Affinity DataIC50: 6.96nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669839(US20240132489, Compound 13 | 4-(6-((1S,4S)-2-oxa-5...)
Affinity DataIC50: 7.05nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669848(US20240132489, Compound 22 | (S)-4-(6-(1,4-oxazepa...)
Affinity DataIC50: 7.05nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669855(US20240132489, Compound 29 | US20240132489, Compou...)
Affinity DataIC50: 7.08nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669840(US20240132489, Compound 14 | (S)-4-(6-(2-oxa-6-aza...)
Affinity DataIC50: 7.11nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669872(US20240132489, Compound 103 | formate )
Affinity DataIC50: 7.26nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669857(US20240132489, Compound 31 | formate )
Affinity DataIC50: 8.13nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669846(US20240132489, Compound 20 | (S)-1-(3-(2-(piperidi...)
Affinity DataIC50: 8.43nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669870(US20240132489, Compound 75 | formate )
Affinity DataIC50: 8.5nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669863(US20240132489, Compound 60 | (S)—N-(6,6-dimet...)
Affinity DataIC50: 8.79nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669847(US20240132489, Compound 21 | (S)-3-methyl-1-(3-(2-...)
Affinity DataIC50: 8.81nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669844(US20240132489, Compound 18 | 4-(6-((S)-3-methylmor...)
Affinity DataIC50: 9.47nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669852(US20240132489, Compound 26 | N—((S)-6,6-dimet...)
Affinity DataIC50: 9.5nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669882(US20240132489, Compound 115 | 4-(6-((S)-3-methylmo...)
Affinity DataIC50: 9.52nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669869(US20240132489, Compound 74 | N-((3S,5R)-5-fluoropy...)
Affinity DataIC50: 10.2nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669828(US20240132489, Compound 2 | 4-(6-((1R,4R)-2-oxa-5-...)
Affinity DataIC50: 10.4nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669832(US20240132489, Compound 6 | 3-methyl-1-(3-(2-(((S)...)
Affinity DataIC50: 10.4nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669856(US20240132489, Compound 30)
Affinity DataIC50: 10.5nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669842(US20240132489, Compound 16 | (S)-4-(6-(1-oxa-7-aza...)
Affinity DataIC50: 10.8nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669868(US20240132489, Compound 73 | N-((3S,5S)-5-fluoropy...)
Affinity DataIC50: 11.5nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669831(US20240132489, Compound 5 | N—((S)-piperidin-...)
Affinity DataIC50: 12.1nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669849(US20240132489, Compound 23 | (S)-4-methyl-1-(3-(2-...)
Affinity DataIC50: 13.1nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669827(US20240132489, Compound 1 | (S)-4-(6-morpholinyl-1...)
Affinity DataIC50: 13.4nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669841(US20240132489, Compound 15 | (S)-4-(6-(2-oxa-7-aza...)
Affinity DataIC50: 16.5nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669829(US20240132489, Compound 3 | amino)-5-(trifluoromet...)
Affinity DataIC50: 17.4nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669830(US20240132489, Compound 4 | amino)-5-(trifluoromet...)
Affinity DataIC50: 17.4nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669838(US20240132489, Compound 12 | (3S,4S)-3-methyl-8-(3...)
Affinity DataIC50: 17.4nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669850(US20240132489, Compound 24 | (S)-4-(6-(4-(oxetan-3...)
Affinity DataIC50: 17.4nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669867(US20240132489, Compound 72 | 4-(6-((S)-3-methylmor...)
Affinity DataIC50: 17.6nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669858(US20240132489, Compound 32 | 4-(6-(2-oxo-5-azabicy...)
Affinity DataIC50: 19.9nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669843(US20240132489, Compound 17 | (S)-4-(6-(6-oxa-2-aza...)
Affinity DataIC50: 20nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669833(US20240132489, Compound 7 | 4-(6-(2-oxa-7-azaspiro...)
Affinity DataIC50: 24.3nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669836(US20240132489, Compound 10 | (S)-4-(6-(9-oxa-2-aza...)
Affinity DataIC50: 27nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669837(US20240132489, Compound 11 | (S)-4-(6-(6-oxa-2-aza...)
Affinity DataIC50: 27.8nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669864(US20240132489, Compound 69 | 4-(6-((S)-3-methylmor...)
Affinity DataIC50: 28.4nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669871(US20240132489, Compound 101)
Affinity DataIC50: 28.5nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669835(US20240132489, Compound 9 | (S)-4-(6-(2-oxa-8-azas...)
Affinity DataIC50: 28.7nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669866(US20240132489, Compound 71 | N—((S)-5,5-diflu...)
Affinity DataIC50: 31.7nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
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TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataIC50: 32.5nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent

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