Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 11853
TargetProtein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653556(US20240059704, Compound B2 | 3-(7′-oxo-7R...)
Affinity DataIC50: 259nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
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TargetProtein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653555(US20240059704, Compound B1 | (S)-3-(7′-oxo-7...)
Affinity DataIC50: 330nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653552(US20240059704, Compound A2 | 3-(7'-oxo-3',4',7',9'...)
Affinity DataIC50: 620nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653551(US20240059704, Compound A1 | 3-(7'-oxo-7',9'-dihyd...)
Affinity DataIC50: 1.10E+3nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653553(US20240059704, Compound A3 | 3-(7'-oxo-7',9'-dihyd...)
Affinity DataIC50: 1.30E+3nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653557(US20240059704, Compound B3 | (S)-3-(5′-fluor...)
Affinity DataIC50: 1.73E+3nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653558(US20240059704, Compound B4 | (S)-3-(6′-oxo-6...)
Affinity DataIC50: 4.33E+3nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653559(US20240059704, Compound B5 | 7′-(2,6-dioxopi...)
Affinity DataIC50: 4.63E+3nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653554(US20240059704, Compound A4 | 3-(7'-oxo-3',4',7',9'...)
Affinity DataIC50: 5.20E+3nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent