Compile Data Set for Download or QSAR
Report error Found 294 Enz. Inhib. hit(s) with all data for entry = 11778
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646556(6-chloro-N-[5-(3- fluoropropyl)-4,6-dimethoxy- pyr...)
Affinity DataIC50: 7nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646601(6-chloro-7- (difluoromethylthio)-N-[5-(2- fluoroet...)
Affinity DataIC50: 7nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646555(6-chloro-N-[5-(2,2- difluoroethyl)-4,6-dimethoxy- ...)
Affinity DataIC50: 8nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646694(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)
Affinity DataIC50: 8nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646563(6-chloro-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimi...)
Affinity DataIC50: 9nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646738(6-bromo-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimid...)
Affinity DataIC50: 9nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646588(6-bromo-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimid...)
Affinity DataIC50: 10nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646548(6-chloro-N-[5-(2- fluoroethoxy)-4,6-dimethoxy- pyr...)
Affinity DataIC50: 11nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646598(N-[5-(2-cyanoethyl)-4,6- dimethoxy-pyrimidin-2-yl]...)
Affinity DataIC50: 11nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646655(6-bromo-N-(4,6-dimethoxy-5- methyl-pyrimidin-2-yl)...)
Affinity DataIC50: 11nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646516(6-chloro-N-[5-(3- fluoropropyl)-4-methoxy- pyrimid...)
Affinity DataIC50: 12nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646557(6-chloro-N-[5-(3,3- difluoropropyl)-4,6- dimethoxy...)
Affinity DataIC50: 12nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646602(6-chloro-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimi...)
Affinity DataIC50: 12nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646551(N-(5-allyl-4,6-dimethoxy- pyrimidin-2-yl)-6-chloro...)
Affinity DataIC50: 13nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646554(6-chloro-N-[5-(2-fluoroethyl)- 4,6-dimethoxy-pyrim...)
Affinity DataIC50: 13nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646606(US20240025883, Example 288 | 6-bromo-N-[5-(2,2- di...)
Affinity DataIC50: 13nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646681(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)
Affinity DataIC50: 13nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646778(US20240025883, Example 283)
Affinity DataIC50: 13nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646564(6-chloro-N-(5-cyclopropyl- 4,6-dimethoxy-pyrimidin...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646597(N-[5-(2,2-difluoroethoxy)-4,6- dimethoxy-pyrimidin...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646600(6-chloro-N-[5-(2-cyanoethyl)- 4-methoxy-pyrimidin-...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646636(7-bromo-6-chloro-N-[5-(2- fluoroethoxy)-4-methoxy-...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646702(6-chloro-N-[5-(3,3- difluoropropyl)-4-methoxy- pyr...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646713(6-chloro-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimi...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646731(N-[5-(2,2-difluoroethyl)-4,6- dimethoxy-pyrimidin-...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646747(US20240025883, Example 253 | N-[5-(2-cyanoethyl)-4...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646760(6-chloro-N-[5- (cyanomethoxy)-4,6- dimethoxy-pyrim...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646667(US20240025883, Example 172)
Affinity DataIC50: 15nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646607(6-bromo-N-[5-(3,3- difluoropropyl)-4,6- dimethoxy-...)
Affinity DataIC50: 16nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646616(6-chloro-N-[5-(3,3- difluoropropyl)-4,6- dimethoxy...)
Affinity DataIC50: 16nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646691(6-bromo-N-[5-(2,2- difluoroethyl)-4-methoxy- pyrim...)
Affinity DataIC50: 16nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646729(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)
Affinity DataIC50: 16nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646739(6-bromo-N-[5- (cyanomethoxy)-4,6- dimethoxy-pyrimi...)
Affinity DataIC50: 16nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646549(6-chloro-N-[5-(2,2- difluoroethoxy)-4,6- dimethoxy...)
Affinity DataIC50: 17nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646550(6-chloro-N-[4,6-dimethoxy-5- (1,1,2- trifluoroetho...)
Affinity DataIC50: 17nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646553(6-chloro-N-(4,6-dimethoxy-5- propyl-pyrimidin-2-yl...)
Affinity DataIC50: 17nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646712(6-chloro-N-[5-(2,2- difluoroethyl)-4,6-dimethoxy- ...)
Affinity DataIC50: 17nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646587(6-bromo-N-[5-(2,2- difluoroethoxy)-4,6- dimethoxy-...)
Affinity DataIC50: 18nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646682(6-chloro-N-[5-(3,3- difluoropropyl)-4-methoxy- pyr...)
Affinity DataIC50: 18nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646705(6,7-dichloro-N-[5-(2,2- difluoroethyl)-4-methoxy- ...)
Affinity DataIC50: 18nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646714(6-chloro-N-[5- (cyanomethoxy)-4,6- dimethoxy-pyrim...)
Affinity DataIC50: 18nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646512(6-chloro-N-(4,6-dimethoxy-5- methyl-pyrimidin-2-yl...)
Affinity DataIC50: 19nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646542(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)
Affinity DataIC50: 19nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646561(6-chloro-N-[4,6-dimethoxy-5- (2-methoxyethyl)pyrim...)
Affinity DataIC50: 19nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646741(6-bromo-N-[5- (cyanomethoxy)-4,6- dimethoxy-pyrimi...)
Affinity DataIC50: 19nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646507(N-(5-bromo-4,6-dimethoxy- pyrimidin-2-yl)-6-chloro...)
Affinity DataIC50: 20nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646664(N-[5-(2,2-difluoroethyl)-4,6- dimethoxy-pyrimidin-...)
Affinity DataIC50: 20nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646687(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)
Affinity DataIC50: 20nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646747(US20240025883, Example 253 | N-[5-(2-cyanoethyl)-4...)
Affinity DataIC50: 20nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646536(6-chloro-N-[4-methoxy-5- (1,1,2- trifluoroethoxy)p...)
Affinity DataIC50: 21nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
Go to US Patent

Displayed 1 to 50 (of 294 total ) | Next | Last >>
Jump to: