Compile Data Set for Download or QSAR
Report error Found 801 Enz. Inhib. hit(s) with all data for entry = 11639
TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635953(US20230365537, Example 78 | (1R,2S)-2-(3-((5-chlor...)
Affinity DataIC50: 0.350nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635903(US20230365537, Example 28 | (1R,2S)-2-(3-{[(3S)-3-...)
Affinity DataIC50: 0.375nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635951(US20230365537, Example 76 | (1R,2S)-2-(3-{[5-chlor...)
Affinity DataIC50: 0.434nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM50073587(CHEMBL3408947 | US9907800, Example A185 | US103584...)
Affinity DataIC50: 0.496nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636141(US20230365537, Example 270 | 5-methoxy-6-({6-[(1R,...)
Affinity DataIC50: 0.564nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636146(US20230365537, Example 275 | 5-ethoxy-6-({6-[(1R,2...)
Affinity DataIC50: 0.590nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636127(US20230365537, Example 256 | (1R,2S)-5'-methoxy-2-...)
Affinity DataIC50: 0.650nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636134(US20230365537, Example 263 | (1R,2S)-2-(3-{[5-(aze...)
Affinity DataIC50: 0.650nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635884(US20230365537, Example 9 | (1R,2S)-2-(3-{[5-chloro...)
Affinity DataIC50: 0.694nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636070(US20230365537, Example 199 | (1R,2S)-5'-methoxy-2-...)
Affinity DataIC50: 0.716nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636116(US20230365537, Example 245 | (1R,2S)-2-[3-({6-[(2R...)
Affinity DataIC50: 0.738nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636145(US20230365537, Example 274 | (1R,2S)-2-(3-{[5-(eth...)
Affinity DataIC50: 0.763nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636135(US20230365537, Example 264 | (1R,2S)-5'-methoxy-2-...)
Affinity DataIC50: 0.785nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636037(US20230365537, Example 166 | 6-methoxy-5-({6-[(1R,...)
Affinity DataIC50: 0.802nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636149(US20230365537, Example 278 | (1R,2S)-2-(3-{[6-(2-h...)
Affinity DataIC50: 0.804nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636077(US20230365537, Example 206 | 2-fluoro-5-methoxy-4-...)
Affinity DataIC50: 0.806nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636075(US20230365537, Example 204 | 5-methoxy-6-({6-[(1R,...)
Affinity DataIC50: 0.810nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635997(US20230365537, Example 125 | (1R,2S)-5'-methoxy-2-...)
Affinity DataIC50: 0.833nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636143(US20230365537, Example 272 | (1R,2S)-2-{3-[2-ethox...)
Affinity DataIC50: 0.833nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636117(US20230365537, Example 246 | (1R,2S)-5'-methoxy-2-...)
Affinity DataIC50: 0.843nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636139(US20230365537, Example 268 | (1R,2S)-2-(3-{[5-(aze...)
Affinity DataIC50: 0.874nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636140(US20230365537, Example 269 | 5-methoxy-6-({6-[(1R,...)
Affinity DataIC50: 0.890nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636079(US20230365537, Example 208 | (1R,2S)-2-{3-[5-fluor...)
Affinity DataIC50: 0.897nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636078(US20230365537, Example 207 | (1R,2S)-2-{3-[5-fluor...)
Affinity DataIC50: 0.952nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636089(US20230365537, Example 218 | N,6-dimethoxy-5-({6-[...)
Affinity DataIC50: 0.955nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636065(US20230365537, Example 194 | 6-methoxy-5-({6-[(1R,...)
Affinity DataIC50: 0.965nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636130(US20230365537, Example 259 | (1R,2S)-5'-methoxy-2-...)
Affinity DataIC50: 0.971nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636026(US20230365537, Example 154 | (1R,2S)-5'-methoxy-2-...)
Affinity DataIC50: 0.976nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636040(US20230365537, Example 169 | (1R,2S)-2-[3-({2-[(3R...)
Affinity DataIC50: 0.995nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635947(US20230365537, Example 72 | (1R,2S)-2-(3-{[5-chlor...)
Affinity DataIC50: 0.997nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636085(US20230365537, Example 214 | 6-ethoxy-5-({6-[(1R,2...)
Affinity DataIC50: 1.01nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636027(US20230365537, Example 155 | (1R,2S)-5'-methoxy-2-...)
Affinity DataIC50: 1.03nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636103(US20230365537, Example 232 | (1R,2S)-5'-methoxy-2-...)
Affinity DataIC50: 1.03nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636060(US20230365537, Example 189 | (1R,2S)-2-(3-{[2-(4,4...)
Affinity DataIC50: 1.04nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636074(US20230365537, Example 203 | 5-ethoxy-6-({6-[(1R,2...)
Affinity DataIC50: 1.04nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636068(US20230365537, Example 197 | 5-methoxy-6-({6-[(1R,...)
Affinity DataIC50: 1.08nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635945(US20230365537, Example 70 | (1R,2S)-2-(3-((5-chlor...)
Affinity DataIC50: 1.10nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636064(US20230365537, Example 193 | (1R,2S)-2-(3-{[5-(met...)
Affinity DataIC50: 1.13nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635972(US20230365537, Example 97 | (1R,2S)-5'-methoxy-2-(...)
Affinity DataIC50: 1.14nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636114(US20230365537, Example 243 | N,N-dicyclopropyl-6-m...)
Affinity DataIC50: 1.15nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636126(US20230365537, Example 255 | (1R,2S)-5'-methoxy-2-...)
Affinity DataIC50: 1.16nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636038(US20230365537, Example 167 | (1R,2S)-5'-methoxy-2-...)
Affinity DataIC50: 1.18nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636088(US20230365537, Example 217 | (1R,2S)-5'-methoxy-2-...)
Affinity DataIC50: 1.19nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635926(US20230365537, Example 51 | (1R,2S)-2-(3-{[2-cyclo...)
Affinity DataIC50: 1.23nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636119(US20230365537, Example 248 | (1R,2S)-5'-methoxy-2-...)
Affinity DataIC50: 1.24nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635928(US20230365537, Example 53 | (1R,2S)-2-(3-((5-chlor...)
Affinity DataIC50: 1.25nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635930(US20230365537, Example 55 | (1R,2S)-2-(3-{[5-(2-hy...)
Affinity DataIC50: 1.25nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636054(US20230365537, Example 183 | (1R,2S)-5'-methoxy-2-...)
Affinity DataIC50: 1.25nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635959(US20230365537, Example 84 | (1R,2S)-2-(3-((6-(1,1-...)
Affinity DataIC50: 1.28nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK4(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635922(US20230365537, Example 47 | (1R,2S)-2-(3-{[5-chlor...)
Affinity DataIC50: 1.30nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent

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