Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 11600
TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631376(US20230348398, Example 22 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 130nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631372(US20230348398, Example 18 | 2-[(4-Benzylpiperazin-...)
Affinity DataIC50: 140nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631361(US20230348398, Example 7 | 6-(2-Chloro-4-methylphe...)
Affinity DataIC50: 260nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631369(US20230348398, Example 15 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 260nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631382(US20230348398, Example 28 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 350nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631378(US20230348398, Example 24 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 360nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631363(US20230348398, Example 9 | 6-(2-Chloro-4-methylphe...)
Affinity DataIC50: 380nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631375(US20230348398, Example 21 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 410nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631377(US20230348398, Example 23 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 480nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631364(US20230348398, Example 10 | 2-[(4-Benzyl-3-oxopipe...)
Affinity DataIC50: 510nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631243(US20230348398, Example 2 | 6-(2-Chloro-5-fluoro-4-...)
Affinity DataIC50: 540nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631367(US20230348398, Example 13 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 550nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631290(US20230348398, Example 3 | 6-(2-Chloro-4-methylphe...)
Affinity DataIC50: 550nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631362(US20230348398, Example 8 | 6-(2-Chloro-4-methylphe...)
Affinity DataIC50: 590nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631383(US20230348398, Example 29 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 590nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631374(US20230348398, Example 20 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 590nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631365(US20230348398, Example 11 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 600nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631379(US20230348398, Example 25 | 2-(Anilinomethyl)-6-(2...)
Affinity DataIC50: 690nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631385(US20230348398, Example 31 | 2-(Benzylamino)-6-(2-c...)
Affinity DataIC50: 840nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631380(US20230348398, Example 26 | 2-Benzyl-6-(2-chloro-4...)
Affinity DataIC50: 1.02E+3nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631366(US20230348398, Example 12 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 1.14E+3nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631368(US20230348398, Example 14 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 1.16E+3nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631371(US20230348398, Example 17 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 1.23E+3nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631373(US20230348398, Example 19 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 1.25E+3nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631381(US20230348398, Example 27 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 1.48E+3nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631370(US20230348398, Example 16 | 2-[(4-Acetylpiperazin-...)
Affinity DataIC50: 1.51E+3nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631360(US20230348398, Example 6 | 6-(4-Chloro-2-methylphe...)
Affinity DataIC50: 2.08E+3nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631386(US20230348398, Example 32 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 2.41E+3nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631384(US20230348398, Example 30 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 3.02E+3nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631359(US20230348398, Example 5 | 6-(2-Chloro-4-(trifluor...)
Affinity DataIC50: 3.26E+3nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631302(US20230348398, Example 4 | 6-(2-Chloro-4-ethoxyphe...)
Affinity DataIC50: 4.37E+3nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631204(US20230348398, Example 1 | 6-(2-Chloro-4-cycloprop...)
Affinity DataIC50: 4.68E+3nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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