Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 11534
LigandPNGBDBM498545((1R,3S)-3-[3-({[2- (methylsulfonyl)phenyl]acetyl}...)
Affinity DataKi:  0.280nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
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Date in BDB:
11/22/2023
Entry Details
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LigandPNGBDBM611576(US11718603, Example 1 | US20230321042, Compound C)
Affinity DataKi:  0.550nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
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Date in BDB:
11/22/2023
Entry Details
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LigandPNGBDBM498185(US11014911, Example 13 | US11718603, Example 13 | ...)
Affinity DataKi:  1.16nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
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Date in BDB:
11/22/2023
Entry Details
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LigandPNGBDBM498545((1R,3S)-3-[3-({[2- (methylsulfonyl)phenyl]acetyl}...)
Affinity DataKi:  107nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
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Date in BDB:
11/22/2023
Entry Details
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LigandPNGBDBM611576(US11718603, Example 1 | US20230321042, Compound C)
Affinity DataKi:  149nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
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Date in BDB:
11/22/2023
Entry Details
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LigandPNGBDBM611576(US11718603, Example 1 | US20230321042, Compound C)
Affinity DataKi:  215nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
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Date in BDB:
11/22/2023
Entry Details
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LigandPNGBDBM498185(US11014911, Example 13 | US11718603, Example 13 | ...)
Affinity DataKi:  243nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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LigandPNGBDBM498545((1R,3S)-3-[3-({[2- (methylsulfonyl)phenyl]acetyl}...)
Affinity DataKi:  254nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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LigandPNGBDBM498185(US11014911, Example 13 | US11718603, Example 13 | ...)
Affinity DataKi:  465nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent