Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 2286
TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615666((5-isopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-(1H-tet...)
Affinity DataIC50: 4nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615641((1-isopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-(1H-te...)
Affinity DataIC50: 10nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615640((1-isopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-([1,2,...)
Affinity DataIC50: 10nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615664((5-isopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-(6-meth...)
Affinity DataIC50: 10nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM608065(US11691968, Example 1 | [(1R,5S,6r)-6-(5,5-dimethy...)
Affinity DataIC50: 20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM608089(US11691968, Example 85 | (1-cyclopropyl-1H-imidazo...)
Affinity DataIC50: 20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615647((1-isopropyl-1H-imidazol-4-yl){(1R,5S,6r)-6-[(4-me...)
Affinity DataIC50: 20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615642((1R,5S,6r)-N-tert-butyl-3-[1-(propan-2-yl)-1H-imid...)
Affinity DataIC50: 20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615638((1-isopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-(4,5,5...)
Affinity DataIC50: 20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM608073(US11691968, Example 51 | (1-cyclopropyl-1H-imidazo...)
Affinity DataIC50: 20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615636((1-isopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-(5-met...)
Affinity DataIC50: 20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615669((5-cyclopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-methy...)
Affinity DataIC50: 20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615656((5-isopropyl-1H-pyrazol-3-yl){(1R,5S,6r)-6-[(1S,5S...)
Affinity DataIC50: 30nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM608071(US11691968, Example 33 | [(1R,5S,6r)-6-(5,5-dimeth...)
Affinity DataIC50: 30nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615643((1R,5S,6r)-N-tert-butyl-N-methyl-3-[1-(propan-2-yl...)
Affinity DataIC50: 30nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615650((1-isopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-methyl...)
Affinity DataIC50: 30nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM608087(US11691968, Example 82 | (1-cyclopropyl-1H-imidazo...)
Affinity DataIC50: 30nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615658({(1R,5S,6r)-6-[5-(difluoromethyl)-4-methyl-1,2-oxa...)
Affinity DataIC50: 40nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615659((5-isopropyl-1H-pyrazol-3-yl){(1R,5S,6r)-6-[5-meth...)
Affinity DataIC50: 40nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615652((1R,5S,6r)-N-tert-butyl-6-methyl-3-[1-(propan-2-yl...)
Affinity DataIC50: 40nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615662((5-isopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-(4-phen...)
Affinity DataIC50: 40nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615663([(1R,5S,6r)-6-(4-cyclobutyl-5-methyl-4H-1,2,4-tria...)
Affinity DataIC50: 40nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615665((5-isopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-([1,2,3...)
Affinity DataIC50: 40nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615660([(1R,5S,6r)-6-(4-ethyl-5,5-dimethyl-4,5-dihydro-1,...)
Affinity DataIC50: 50nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615654([5-(1-cyclopropylethyl)-1H-pyrazol-3-yl][(1R,5S,6r...)
Affinity DataIC50: 50nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615667((1R,5S,6r)-N-(propan-2-yl)-3-[5-(propan-2-yl)-1H-p...)
Affinity DataIC50: 50nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM608067(US11691968, Example 12 | {1-[(2S)-butan-2-yl]-1H-i...)
Affinity DataIC50: 60nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM608086(US11691968, Example 81 | [(1R,5S,6r)-6-(5,5-dimeth...)
Affinity DataIC50: 60nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615646((1-isopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-(2-thi...)
Affinity DataIC50: 60nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM608091(US11691968, Example 88 | [(1R,5S,6r)-6-(5,5-dimeth...)
Affinity DataIC50: 70nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615670((1R,5S,6r)-N-tert-butyl-6-methyl-3-[5-(propan-2-yl...)
Affinity DataIC50: 90nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615657((5-isopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-(5-meth...)
Affinity DataIC50: 200nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615655((5-isopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-(5-meth...)
Affinity DataIC50: 200nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615644((1R,5S,6r)-N-(1-cyanocyclopropyl)-N-methyl-3-[1-(p...)
Affinity DataIC50: 200nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615639([(1R,5S,6r)-6-(4-ethyl-5,5-dimethyl-4,5-dihydro-1,...)
Affinity DataIC50: 200nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615637((1-isopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-(5-met...)
Affinity DataIC50: 200nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615634({(1R,5S,6r)-6-[5-(difluoromethyl)-5-methyl-4,5-dih...)
Affinity DataIC50: 200nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615631(4-[(1S)-1-(4-{[(1R,5S,6S)-6-(5,5-dimethyl-4,5-dihy...)
Affinity DataIC50: 200nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615661((5-isopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-(5-meth...)
Affinity DataIC50: 300nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615645(cyclopropyl{(1R,5S,6r)-3-[(1-isopropyl-1H-imidazol...)
Affinity DataIC50: 400nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615630(2-[(1S)-1-(4-{[(1R,5S,6S)-6-(5,5-dimethyl-4,5-dihy...)
Affinity DataIC50: 400nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615628([(1R,5S,6r)-6-(5,5-dimethyl-4,5-dihydro-1,2-oxazol...)
Affinity DataIC50: 400nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615668((1R,5S,6r)-N-methyl-N-(1-methylcyclopropyl)-3-[5-(...)
Affinity DataIC50: 800nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615632([(1R,5S,6S)-6-(5,5-dimethyl-4,5-dihydro-1,2-oxazol...)
Affinity DataIC50: 1.00E+3nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent