Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 12671
TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719050(Preparation of N-(2-(6-fluoro-1H-indol-3-yl)ethyl)...)
Affinity DataIC50: 63.1nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719046(Preparation of N-(2-(1H-indol-3-yl)ethyl)-2-(5-chl...)
Affinity DataIC50: 63.1nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719045(N-(2-(1H-indol-3-yl)ethyl)-2-(5-methylpyridin-3-yl...)
Affinity DataIC50: 63.1nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719051(N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-2-(5-fluoropyr...)
Affinity DataIC50: 79.4nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719025(N-(2-(1H-indol-3-yl)ethyl)-2-(5-fluoropyridin-3-yl...)
Affinity DataIC50: 100nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719033(1-(4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropy...)
Affinity DataIC50: 100nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719020(5-(4-((2-(1H-indol-3-yl)ethyl)amino)-7-(cyanomethy...)
Affinity DataIC50: 158nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719027(N-(2-(1H-indol-3-yl)ethyl)-2-(pyridin-3-yl)-6,7-di...)
Affinity DataIC50: 158nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719042(Preparation of 5-(4-((2-(1H-indol-3-yl)ethyl)amino...)
Affinity DataIC50: 200nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719024(N-(2-(1H-indol-3-yl)ethyl)-2-(pyridin-3-yl)-5,6,7,...)
Affinity DataIC50: 200nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719048(Preparation of N-(2-(6-fluoro-1H-indol-3-yl)ethyl)...)
Affinity DataIC50: 200nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
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TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719026(N-(2-(1H-indol-3-yl)ethyl)-2-(pyridin-3-yl)-5,6,7,...)
Affinity DataIC50: 251nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719043(N-(2-(1H-indol-3-yl)ethyl)-2-(5-fluoropyridin-3-yl...)
Affinity DataIC50: 251nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719049(Preparation of N-(2-(5-fluoro-1H-indol-3-yl)ethyl)...)
Affinity DataIC50: 316nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719041(Preparation of N-(2-(1H-indol-3-yl)ethyl)-2-(5-chl...)
Affinity DataIC50: 316nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719023(N-(2-(1H-indol-3-yl)ethyl)-2-(5-fluoropyridin-3-yl...)
Affinity DataIC50: 316nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719028(4-(2-(1H-indol-3-yl)ethoxy)-2-(5-fluoropyridin-3-y...)
Affinity DataIC50: 398nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719022(N-(2-(1H-indol-3-yl)ethyl)-2-(5-fluoropyridin-3-yl...)
Affinity DataIC50: 398nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719040(Preparation of N-(2-(1H-indol-3-yl)ethyl)-2-(5-flu...)
Affinity DataIC50: 398nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719039(Preparation of N-(2-(1H-indol-3-yl)ethyl)-2-(5-met...)
Affinity DataIC50: 398nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719019(N-(2-(1H-indol-3-yl)ethyl)-2-(5-fluoropyridin-3-yl...)
Affinity DataIC50: 631nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719044(N-(2-(1H-indol-3-yl)ethyl)-2-(5-fluoropyridin-3-yl...)
Affinity DataIC50: 631nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719036(N-(2-(1H-indol-3-yl)ethyl)-7-benzyl-2-(5-fluoropyr...)
Affinity DataIC50: 631nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719034(US12221439, Example 17a)
Affinity DataIC50: 631nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719035(US12221439, Example 17b)
Affinity DataIC50: 794nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719031(4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropyrid...)
Affinity DataIC50: 794nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719029(4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropyrid...)
Affinity DataIC50: 794nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719021(2-(4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropy...)
Affinity DataIC50: 794nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719032(Preparation of (4-((2-(1H-indol-3-yl)ethyl)amino)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719018(1-(4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropy...)
Affinity DataIC50: 1.00E+3nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719037(N-(2-(1H-indol-3-yl)ethyl)-2-(5-fluoropyridin-3-yl...)
Affinity DataIC50: 1.26E+3nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719030(4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropyrid...)
Affinity DataIC50: 2.00E+3nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719047(Preparation of N-(2-(1H-benzo[d]imidazol-2-yl)ethy...)
Affinity DataIC50: 3.16E+3nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719038(Preparation of N-(2-(1H-benzo[d]imidazol-2-yl)ethy...)
Affinity DataIC50: 7.94E+3nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent