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Found
232
Enz. Inhib. hit(s) with all data for entry = 12535
Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709139
(6-[5-({[3-(cyclobutylmeth-oxy)phenyl]methyl}carbam...)
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Affinity Data
IC50: 0.0400nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709106
(6-(5-{[(2-ethylphenyl)methyl]-carbamoyl}-6-methoxy...)
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Affinity Data
IC50: 0.400nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709075
(6-[6-methoxy-5-({[(1S,2R)-2-phenylcyclopropyl]meth...)
Copy SMILES
Affinity Data
IC50: 0.700nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709117
(6-[6-methoxy-5-({[2-(propan-2-yloxy)phenyl]methyl}...)
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Affinity Data
IC50: 1.30nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709104
(6-[6-methoxy-5-({[2-(propane-2-sulfonyl)phenyl]met...)
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Affinity Data
IC50: 1.40nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709161
(6-[5-({[2-fluoro-5-(trifluoro-methoxy)phenyl]methy...)
Copy SMILES
Affinity Data
IC50: 1.60nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709072
(6-{6-methoxy-5-[(3-phenylbutyl)-carbamoyl]pyridin-...)
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Affinity Data
IC50: 1.70nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709076
(6-[6-methoxy-5-({[(1R,2S)-2-phenylcyclopropyl]meth...)
Copy SMILES
Affinity Data
IC50: 1.80nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709099
(6-[6-methoxy-5-({[2-(2,2,2-trifluoroethoxy)phenyl]...)
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Affinity Data
IC50: 1.80nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709103
(6-(6-methoxy-5-{[(2-phenyl-oxan-3-yl)methyl]carbam...)
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Affinity Data
IC50: 1.80nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709115
(6-{5-[(2-{[(4-fluorophenyl)-methyl]carbamoyl}-2,2-...)
Copy SMILES
Affinity Data
IC50: 1.80nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709154
(6-[5-({[5-fluoro-2-(propan-2-yloxy)phenyl]methyl}c...)
Copy SMILES
Affinity Data
IC50: 1.90nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM707964
(US12172975, Example 21-4)
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Affinity Data
IC50: 2nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709181
(6-[5-({[2-(cyclopentyloxy)-5-fluoro-phenyl]methyl}...)
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Affinity Data
IC50: 2.10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM707954
(6-(6-methoxy D3-5-((2-(trifluoromethoxy)benzyl D2)...)
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Affinity Data
IC50: 2.20nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709066
(6-(5-{[(1R)-1-[2-fluoro-5-(tri-fluoromethyl)phenyl...)
Copy SMILES
Affinity Data
IC50: 2.30nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709087
(6-(5-{[3-(4-fluorophenoxy)-propyl]carbamoyl}-6-met...)
Copy SMILES
Affinity Data
IC50: 2.30nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709151
(6-[5-({[2-fluoro-6-(propan-2-yloxy)phenyl]methyl}-...)
Copy SMILES
Affinity Data
IC50: 2.30nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709152
(6-[5-({[2-(cyclopropylmeth-oxy)-3,5-difluorophenyl...)
Copy SMILES
Affinity Data
IC50: 2.30nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709074
(6-[5-({[4-fluoro-2-(oxan-4-yl-oxy)phenyl]methyl}ca...)
Copy SMILES
Affinity Data
IC50: 2.40nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709110
(6-[5-({[2-(cyclobutylmethoxy)-phenyl]methyl}carbam...)
Copy SMILES
Affinity Data
IC50: 2.40nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709062
(6-(5-{[(3S)-3-(4-chlorophenyl)-3-hydroxypropyl]car...)
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Affinity Data
IC50: 2.5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709077
(6-[6-methoxy-5-([2-(morpholin-4-yl)phenyl]methyl}c...)
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Affinity Data
IC50: 2.60nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709141
(6-[5-({[3-(cyclobutylmethoxy)-pyridin-2-yl]methyl}...)
Copy SMILES
Affinity Data
IC50: 2.60nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709102
(6-[5-({[2-(difluoromethoxy)-phenyl]methyl}carbamoy...)
Copy SMILES
Affinity Data
IC50: 2.70nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709116
(6-[6-methoxy-5-({[3-(trifluoro-methoxy)phenyl]meth...)
Copy SMILES
Affinity Data
IC50: 2.80nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709083
(6-[6-methoxy-5-({[2-(2-meth-ylpropoxy)phenyl]methy...)
Copy SMILES
Affinity Data
IC50: 2.90nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709177
(6-[6-methoxy-5-({[2-(trifluoro-methoxy)phenyl]{met...)
Copy SMILES
Affinity Data
IC50: 2.90nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709178
(N-methyl-6-(6-methyl-5-{[(1S,3R)-3-phenylcyclopent...)
Copy SMILES
Affinity Data
IC50: 2.90nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709201
(6-[6-methoxy-5-({[2-(trifluoro-methoxy)phenyl]meth...)
Copy SMILES
Affinity Data
IC50: 2.90nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709105
(6-(5-{[(2,2-dimethylcyclo-hexyl)methyl]carbamoyl}-...)
Copy SMILES
Affinity Data
IC50: 3.10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709081
(6-{5-[({2-[4-(hydroxymethyl)-piperidin-1-yl]phenyl...)
Copy SMILES
Affinity Data
IC50: 3.40nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM707961
(US12172975, Example 21-1)
Copy SMILES
Affinity Data
IC50: 3.5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM707948
((S)-6-(5-((1-(2-fluoro-5-(trifluoromethoxy)phenyl)...)
Copy SMILES
Affinity Data
IC50: 3.70nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709109
(6-[5-({[2-(cyclopropylsulfam-oyl)phenyl]methyl}car...)
Copy SMILES
Affinity Data
IC50: 3.70nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709180
(N-methyl-6-[6-methyl-5-({1-[3-(tri-fluoromethoxy)p...)
Copy SMILES
Affinity Data
IC50: 3.70nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709101
(tert-butyl N-[(1R,2S)-2-[({2-methoxy-5-[3-(methylc...)
Copy SMILES
Affinity Data
IC50: 3.80nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709111
(6-(6-methoxy-5-{[3-(2,2,2-trifluoroethoxy)cyclohex...)
Copy SMILES
Affinity Data
IC50: 3.90nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709239
(6-(5-{[(1R)-1-[2-fluoro-5-(trifluoro-methyl)phenyl...)
Copy SMILES
Affinity Data
IC50: 3.90nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM707944
((R)-6-(5-((1-(2-fluoro-5-(trifluoromethyl)phenyl) ...)
Copy SMILES
Affinity Data
IC50: 4.20nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709150
(6-[5-({[3,5-difluoro-2-(propan-2-yloxy)phenyl]meth...)
Copy SMILES
Affinity Data
IC50: 4.20nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709093
(6-[6-methoxy-5-({[2-(propane-1-sulfonyl)phenyl]met...)
Copy SMILES
Affinity Data
IC50: 4.5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709125
(6-[6-methoxy-5-({1-[3-(tri-fluoromethyl)phenyl]eth...)
Copy SMILES
Affinity Data
IC50: 4.5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709092
(6-[6-methoxy-5-({[1-(phenoxy-methyl)cyclopropyl]me...)
Copy SMILES
Affinity Data
IC50: 4.60nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709091
(6-(6-methoxy-5-{[(1S,3R)-3-phenylcyclopentyl]carba...)
Copy SMILES
Affinity Data
IC50: 4.70nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709097
(tert-butyl-N-{2-[({2-methoxy-5-[3-(methylcarbamoyl...)
Copy SMILES
Affinity Data
IC50: 4.70nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709136
(6-[5-({[2-(cyclobutylmeth-oxy)pyridin-3-yl]methyl}...)
Copy SMILES
Affinity Data
IC50: 4.80nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM707953
(6-(6-methoxy d3-5-((1-(2-(trifluoromethoxy)phenyl)...)
Copy SMILES
Affinity Data
IC50: 5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM709090
(6-(5-{[(2-methanesulfonyl-phenyl)methyl]carbamoyl}...)
Copy SMILES
Affinity Data
IC50: 5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Copy BDB DOI
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Human)
TBA
Ligand
BDBM707967
(4-fluoro-6-[6-methoxy-5-({1-[2-(trifluoromethoxy)p...)
Copy SMILES
Affinity Data
IC50: 5.40nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
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