Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 12398
TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700719(US12115157, Ex. 11a)
Affinity DataEC50:  1.28E+3nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700730(US12115157, Int. H-3)
Affinity DataEC50:  378nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700729(US12115157, Ex. 16b)
Affinity DataEC50:  210nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700728(BDBM700731 | (S)—N-(3-cyano-4-fluorophenyl)-1,2,4-...)
Affinity DataEC50:  11nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700727(US12115157, Ex. 15b)
Affinity DataEC50:  168nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700726(US12115157, Ex. 15a)
Affinity DataEC50:  20nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700725(US12115157, Ex. 14b)
Affinity DataEC50:  11nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700724(US12115157, Ex. 14a)
Affinity DataEC50:  1.17E+3nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700723(US12115157, Ex. 13b)
Affinity DataEC50:  3nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700722(US12115157, Ex. 13a)
Affinity DataEC50:  595nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700721(US12115157, Ex. 12)
Affinity DataEC50:  24nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700720(US12115157, Ex. 11b)
Affinity DataEC50:  10nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700707(US12115157, Ex. 1)
Affinity DataEC50:  15nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700718(US12115157, Ex. 10b)
Affinity DataEC50:  1.33E+3nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700717(US12115157, Ex. 10a)
Affinity DataEC50:  14nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700716(US12115157, Ex. 9)
Affinity DataEC50:  19nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700715(US12115157, Ex. 8b)
Affinity DataEC50:  7nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700714(US12115157, Ex. 8a)
Affinity DataEC50:  1.09E+3nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700713(US12115157, Ex. 7)
Affinity DataEC50:  102nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700712(US12115157, Ex. 6)
Affinity DataEC50:  54nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700711(US12115157, Ex. 5)
Affinity DataEC50:  27nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700710(US12115157, Ex. 4)
Affinity DataEC50:  18nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700709(US12115157, Ex. 3)
Affinity DataEC50:  92nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetG-protein coupled receptor 52(Human)
Boehringer Ingelheim International GmbH; Arena Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM700708(US12115157, Ex. 2)
Affinity DataEC50:  24nMAssay Description:HTRF cAMP assays were performed using commercially available assay kits according to the manufacturer's instructions (cAMP Dynamic 2 Assay Kit; #...More data for this Ligand-Target Pair
In DepthDetails
US Patent