Compile Data Set for Download or QSAR
Report error Found 59 Enz. Inhib. hit(s) with all data for entry = 12234
TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689138(US12049474, Compound B1-1-024)
Affinity DataIC50: 2.39E+3nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689155(US12049474, Compound MD-1-119)
Affinity DataIC50: 1.10E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689145(US12049474, Compound NP-PD-149)
Affinity DataIC50: 1.20E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
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TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689141(US12049474, Compound NP-PD-051)
Affinity DataIC50: 1.64E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689138(US12049474, Compound B1-1-024)
Affinity DataIC50: 1.87E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689150(US12049474, Compound MD-1-124)
Affinity DataIC50: 1.92E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689147(US12049474, Compound NP-PD-130)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689142(US12049474, Compound NP-PD-102)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689142(US12049474, Compound NP-PD-102)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689143(US12049474, Compound NP-PD-105)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689144(US12049474, Compound MD-5-72)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689144(US12049474, Compound MD-5-72)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689145(US12049474, Compound NP-PD-149)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689146(US12049474, Compound NP-PD-158)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689146(US12049474, Compound NP-PD-158)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689143(US12049474, Compound NP-PD-105)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689148(US12049474, Compound MD-1-122)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689148(US12049474, Compound MD-1-122)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689149(US12049474, Compound MD-1-221)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689149(US12049474, Compound MD-1-221)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689152(US12049474, Compound MD-1-183)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689153(US12049474, Compound MD-1-184)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689154(US12049474, Compound MD-1-187)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689154(US12049474, Compound MD-1-187)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689156(US12049474, Compound MD-1-223)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689156(US12049474, Compound MD-1-223)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689133(US12049474, Compound MD-1-105)
Affinity DataIC50: 2.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689151(US12049474, Compound BI-1-057)
Affinity DataIC50: 2.02E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689136(US12049474, Compound EJM-8-036)
Affinity DataIC50: 2.06E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689130(US12049474, Compound TAF)
Affinity DataIC50: 2.10E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689147(US12049474, Compound NP-PD-130)
Affinity DataIC50: 2.17E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689137(US12049474, Compound B1-1-065)
Affinity DataIC50: 2.19E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689134(US12049474, Compound EJM-8-030 | US12049474, Compo...)
Affinity DataIC50: 2.20E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689140(US12049474, Compound NP-PD-042)
Affinity DataIC50: 2.70E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689140(US12049474, Compound NP-PD-042)
Affinity DataIC50: 2.71E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689155(US12049474, Compound MD-1-119)
Affinity DataIC50: 3.63E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689151(US12049474, Compound BI-1-057)
Affinity DataIC50: 3.70E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689134(US12049474, Compound EJM-8-030 | US12049474, Compo...)
Affinity DataIC50: 3.83E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689150(US12049474, Compound MD-1-124)
Affinity DataIC50: 4.08E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM50450813(CHEBI:63625 | Atripla | GS-1275 | PMP-A | Tenofovi...)
Affinity DataIC50: 4.58E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM689130(US12049474, Compound TAF)
Affinity DataIC50: 5.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689137(US12049474, Compound B1-1-065)
Affinity DataIC50: 5.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Emory University

US Patent
LigandPNGBDBM50450813(CHEBI:63625 | Atripla | GS-1275 | PMP-A | Tenofovi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689141(US12049474, Compound NP-PD-051)
Affinity DataIC50: 5.14E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689134(US12049474, Compound EJM-8-030 | US12049474, Compo...)
Affinity DataIC50: 5.22E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689133(US12049474, Compound MD-1-105)
Affinity DataIC50: 5.29E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM77092(CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...)
Affinity DataIC50: 5.33E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM77092(CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...)
Affinity DataIC50: 5.33E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Emory University

US Patent
LigandPNGBDBM689139(US12049474, Compound EJM-8-006)
Affinity DataIC50: 5.48E+4nMAssay Description:Test compounds were prepared in 100% DMSO or 100% MeOH and did not exceed a final concentration of <0.2% in the final reaction. A 100 mM sodium phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

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