Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 11703
TargetMitogen-activated protein kinase 1(Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM175242(US9115089, 49 | US11844801, Compound (M)-I)
Affinity DataIC50: 21nMAssay Description:Inhibition of MK2 and PRAK by Compound (P)-I and (M)-I, respectively, was investigated to understand selectivity of Compound (P)-I and/or Compound (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 1(Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM175242(US9115089, 49 | US11844801, Compound (M)-I)
Affinity DataIC50: 3.48E+3nMAssay Description:Inhibition of MK2 and PRAK by Compound (P)-I and (M)-I, respectively, was investigated to understand selectivity of Compound (P)-I and/or Compound (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2024
Entry Details
Go to US Patent

TargetMAP kinase-activated protein kinase 5(Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM175242(US9115089, 49 | US11844801, Compound (M)-I)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of MK2 and PRAK by Compound (P)-I and (M)-I, respectively, was investigated to understand selectivity of Compound (P)-I and/or Compound (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2024
Entry Details
Go to US Patent

TargetMAP kinase-activated protein kinase 5(Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM175242(US9115089, 49 | US11844801, Compound (M)-I)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of MK2 and PRAK by Compound (P)-I and (M)-I, respectively, was investigated to understand selectivity of Compound (P)-I and/or Compound (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2024
Entry Details
Go to US Patent