Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 11551
TargetProstaglandin G/H synthase 2(Human)
King Faisal University

US Patent
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 20nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
King Faisal University

US Patent
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 25nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
King Faisal University

US Patent
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 45nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Human)
King Faisal University

US Patent
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 50nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
King Faisal University

US Patent
LigandPNGBDBM626239(US11786535, Compound 3)
Affinity DataIC50: 60nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 2(Human)
King Faisal University

US Patent
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 72.5nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
King Faisal University

US Patent
LigandPNGBDBM626238(US11786535, Compound 2)
Affinity DataIC50: 80nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 2(Human)
King Faisal University

US Patent
LigandPNGBDBM626240(US11786535, Compound 4)
Affinity DataIC50: 97nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Human)
King Faisal University

US Patent
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 100nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 2(Human)
King Faisal University

US Patent
LigandPNGBDBM626237(US11786535, Compound 1)
Affinity DataIC50: 210nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Human)
King Faisal University

US Patent
LigandPNGBDBM626237(US11786535, Compound 1)
Affinity DataIC50: 7.62E+3nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Human)
King Faisal University

US Patent
LigandPNGBDBM626240(US11786535, Compound 4)
Affinity DataIC50: 9.19E+3nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Human)
King Faisal University

US Patent
LigandPNGBDBM626238(US11786535, Compound 2)
Affinity DataIC50: 1.06E+4nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Human)
King Faisal University

US Patent
LigandPNGBDBM626239(US11786535, Compound 3)
Affinity DataIC50: 1.15E+4nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Human)
King Faisal University

US Patent
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 1.45E+4nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Human)
King Faisal University

US Patent
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.47E+4nMAssay Description:The inhibitory effects of candidate compounds on COX-1 and COX-2 were determined using COX inhibitor screening test kits, testing each compound's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent