Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 11398
TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612002(US11718619, Compound I-48)
Affinity DataEC50:  6.31nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611987(US11718619, Compound I-33)
Affinity DataEC50: >3.16E+4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611988(US11718619, Compound I-34)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611989(US11718619, Compound I-35)
Affinity DataEC50:  15.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611990(US11718619, Compound I-36)
Affinity DataEC50:  50.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611991(US11718619, Compound I-37)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611992(US11718619, Compound I-38)
Affinity DataEC50:  251nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611993(US11718619, Compound I-39)
Affinity DataEC50:  158nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611994(US11718619, Compound I-40)
Affinity DataEC50:  63.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611995(US11718619, Compound I-41)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611996(US11718619, Compound I-42)
Affinity DataEC50:  10nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611997(US11718619, Compound I-43)
Affinity DataEC50:  50.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611998(US11718619, Compound I-44)
Affinity DataEC50:  12.6nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611999(US11718619, Compound I-45)
Affinity DataEC50:  5.01nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612000(US11718619, Compound I-46)
Affinity DataEC50:  6.31nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612001(US11718619, Compound I-47)
Affinity DataEC50:  15.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611986(US11718619, Compound I-32)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612003(US11718619, Compound I-49)
Affinity DataEC50:  10nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612004(US11718619, Compound I-51)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612005(US11718619, Compound I-52)
Affinity DataEC50:  50.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612006(US11718619, Compound I-53)
Affinity DataEC50:  126nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612007(US11718619, Compound I-54)
Affinity DataEC50:  631nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612008(US11718619, Compound I-55)
Affinity DataEC50: <3.16E+4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612009(US11718619, Compound I-56)
Affinity DataEC50:  251nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612010(US11718619, Compound I-57)
Affinity DataEC50:  1.00E+3nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612011(US11718619, Compound I-58)
Affinity DataEC50: <3.98E+4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612012(US11718619, Compound I-59)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612013(US11718619, Compound I-60)
Affinity DataEC50:  100nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612014(US11718619, Compound I-61)
Affinity DataEC50:  79.4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612015(US11718619, Compound I-62)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612016(US11718619, Compound I-63)
Affinity DataEC50: <316nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612017(US11718619, Compound I-64)
Affinity DataEC50:  251nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611971(US11718619, Compound I-17)
Affinity DataEC50:  31.6nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611956(US11718619, Compound I-2)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611957(US11718619, Compound I-3)
Affinity DataEC50:  126nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611958(US11718619, Compound I-4)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611959(US11718619, Compound I-5)
Affinity DataEC50:  126nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611960(US11718619, Compound I-6)
Affinity DataEC50:  20nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611961(US11718619, Compound I-7)
Affinity DataEC50:  79.4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611962(US11718619, Compound I-8)
Affinity DataEC50:  10nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611963(US11718619, Compound I-9)
Affinity DataEC50:  12.6nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611964(US11718619, Compound I-10)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611965(US11718619, Compound I-11)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611966(US11718619, Compound I-12)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611967(US11718619, Compound I-13)
Affinity DataEC50:  200nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611968(US11718619, Compound I-14)
Affinity DataEC50:  25.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611969(US11718619, Compound I-15)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611970(US11718619, Compound I-16)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611955(US11718619, Compound I-1)
Affinity DataEC50:  316nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611972(US11718619, Compound I-18)
Affinity DataEC50:  200nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent

Displayed 1 to 50 (of 63 total ) | Next | Last >>
Jump to: